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MetabolomicsMetabolic Dynamics of In Vitro CD8+ T Cell Activation

CD8+ T cells detect and kill virally infected or cancerous cells. When activated from their naïve state, T cells undergo a complex transition, including major metabolic reprogramming. Detailed resolution of metabolic dynamics of a wide range of metabolites is needed to advance the field of immuno...

2021-06-02 | MTBLS2145 | MetaboLights
MetabolomicsMicrobial liberation of N-methylserotonin from orange fiber in gnotobiotic mice and humans
Plant fibers in byproduct streams produced by non-harsh food processing methods represent biorepositories of diverse, naturally occurring, and physiologically active biomolecules. To demonstrate one approach for their characterization, mass spectrometry of intestinal contents from gnotobiotic mice, ...
2022-07-28 | MTBLS2331 | MetaboLights
UnknownFine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.
Not available
S-EPMC5995836 | biostudies-literature
UnknownMultiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans.
Not available
S-EPMC4572072 | biostudies-literature
TranscriptomicsInhibition of the mitochondrial TCA cycle by monofluoroacetate in Arabidopsis thaliana
Plant mitochondria signal to the nucleus leading to altered transcription of nuclear genes by a process called mitochondrial retrograde regulation (MRR). MRR is implicated in metabolic homeostasis and responses to stress conditions. Transcriptional consequences on nuclear gene expression of mitochon...
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29268 | biostudies-arrayexpress
ProteomicsDistinct branches of the N-end rule pathway modulate the plant immune response
The N-end rule pathway is a highly conserved constituent of the ubiquitin proteasome system, though little information exists regarding biological roles. Here we show that the cysteine (Cys-) and glutamine (Gln)-specific amino-terminal (Nt)-amidase NTAQ1 branches are both components of the plant imm...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-11-06 | PXD008520 | Pride
Ntaq N-end rule pathway Plant immunity Erfvii Amino-terminal glutamine amidase 
TranscriptomicsTranscription profiling of EhV-86 Infection of E. huxleyi 1516
Not available
ORGANISM(S): Emiliania huxleyi 
2013-01-30 | E-MAXD-8 | biostudies-arrayexpress
UnknownMulti-ancestry genome-wide association meta-analysis of Parkinson's disease.
Not available
S-EPMC10786718 | biostudies-literature
UnknownDiversity and Scale: Genetic Architecture of 2,068 Traits in the VA Million Veteran Program.
Not available
S-EPMC10327290 | biostudies-literature
TranscriptomicsmodENCODE RNA-Seq of Drosophila cell lines Kc167, CME_W1_Cl.8+, S2-DRSC and ML-DmBG3-c2
Deep Sequencing of mRNA from the Drosophila melanogaster cell lines Kc167, CME_W1_Cl.8+, S2-DRSC and ML-DmBG3-c2. For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf Analysis of pol...
ORGANISM(S): Drosophila melanogaster 
2009-04-08 | E-GEOD-15596 | biostudies-arrayexpress
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