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We have employed a scRANSeq to study the difference between WT and Fip200-deficient B cell populations from mice spleen 11 days after immunization. FIP200 plays an important role in regulating LC3-dependent and LC3-independent autophage pathway, which is crucial for B cell development and differenti...
ORGANISM(S): Mus musculus 
Cytosolic dsRNA-induced gene expression in mouse RAW24.7 macrophages and FIP200 knockout RAW cells
Our preliminary data showed that FIP200 is essential for dsRNA-induced interferon production. To corroborate the role of FIP200 in RIG-I signaling pathway, we are going to examine the cytosolic dsRNA-induced gene expression in mouse RAW24.7 macrophages and FIP200 knockout RAW cells.
ORGANISM(S): Mus musculus 
2020-03-16 | GSE147001 | GEO
scRNASeq of Naïve, GC, plasma, memory B cells sorted from WT and Fip200-deficient mice spleen
FIP200 (also known as RB1CC1) has been implicated in a number of psychiatric disorders. The current project aims to characterize the membranomic changes in neurons due to FIP200 loss of function. To this end, two isogenic human pluripotent stem cell (hPSC) lines with FIP200 KO mutations in exon 4 we...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-05 | MSV000091643 | MassIVE
GFP or GFP-200 proteins were purified from the corresponding Flp-In™ T REx™ 293 cells using GFP-Trap beads. Purified proteins were analyzed by mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2021-07-01 | PXD022563 | Pride
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