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TranscriptomicsRNAseq of human Ewing, MSC, fibroblast cell lines - A side population of Ewing cells exhibits stem cell properties
Ewings Sarcoma (ES) belongs to the group of bone cancers defined by the existence of a certain EWS-ETS fusion gene. In this study we use the model cell line CADO-ES1 (EWSR1-ERG fusion gene) to characterize the tumor biology of a versatile ES side-population (SP). We aim to compare SP- and non-SP-cel...
ORGANISM(S): Homo sapiens 
2017-10-31 | E-MTAB-6067 | biostudies-arrayexpress
ProteomicsSmall proteins in a simplified human gut microbiome
Small proteins (sProteins) with a size of 100 amino acids and less are involved in major biological processes and play an important role in different bacteria. Despite the increasing interest in them, the data on sProteins in bacterial communities, like the human gut microbiome is sparse. A reason f...
ORGANISM(S): Blautia producta ATCC 27340 = DSM 2950 Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) Anaerostipes caccae DSM 14662 Clostridium butyricum DSM 10702 Escherichia coli str. K-12 substr. MG1655 Bifidobacterium longum NCC2705 Erysipelatoclostridium ramosum DSM 1402 Lactobacillus plantarum subsp. plantarum 
2020-01-07 | PXD016298 | Pride
Sihumix Small proteins Lc-ms/ms Metaproteomics 
ProteomicsDirect mapping of peptide-spectral-matches to genome information facilitates qualifying proteomics information
The data set consist of three different sources. 1) All files with ecoli_* derive from a pure culture of Escherichia coli K-12 (MG1655). 2) All files with SIHUMI_standard_* derive from a mixed culture of 8 bacteria (SIHUMIx) Anaerostipes caccae (DSMZ 14662), Bacteroides thetaiotaomicron (DSMZ 2079),...
ORGANISM(S): Blautia producta ATCC 27340 = DSM 2950 Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) Lactobacillus plantarum subsp. plantarum ATCC 14917 = JCM 1149 = CGMCC 1.2437 Anaerostipes caccae DSM 14662 Clostridium butyricum DSM 10702 Bifidobacterium longum NCC2705 Escherichia coli str. K-12 substr. MG1655 Erysipelatoclostridium ramosum DSM 1402 
2021-09-09 | PXD023243 | Pride
Intestine Metaomics Sihumi Proteome 
TranscriptomicsRNA-seq analysis of ID8 ovarian cancer cells after harvest from malignant ascites
Sequencing of mRNA from ID8 tumor cells and ID8 tumor cells harvested from ascites of mice 11 weeks after intra peritoneal inoculation show acquisition of cancer stem cell-like features in ascitic tumor cells.
ORGANISM(S): Mus musculus 
2020-01-06 | E-MTAB-8140 | biostudies-arrayexpress
TranscriptomicsHost cell-free growth of the Q fever bacterium Coxiella burnetii
The inability to propagate obligate intracellular pathogens under axenic (host cell-free) culture conditions imposes severe experimental constraints that have negatively impacted progress in understanding pathogen virulence and disease mechanisms. Coxiella burnetii, the causative agent of human Q (Q...
ORGANISM(S): Coxiella burnetii 
2010-06-20 | E-GEOD-13338 | biostudies-arrayexpress
UnknownContested science: Individuals with higher metacognitive insight into interpretation of evidence are less likely to polarize.
Not available
S-EPMC8555729 | biostudies-literature
TranscriptomicsRNA-seq analysis of macrophages from normal and tumor-infiltrated omentum
Sequencing of mRNA from tissue-resident and tumor-associated macrophages in murine omentum display distinct transcriptional profile between macrophage subset of different origin
ORGANISM(S): Mus musculus 
2020-01-06 | E-MTAB-8141 | biostudies-arrayexpress
TranscriptomicsHuman skeletal muscle biopsies from a 3h IL-6 infusion
Skeletal muscle has been identified as a secretory organ. We hypothesized that IL-6, a cytokine secreted from skeletal muscle during exercise, could induce production of other secreted factors in skeletal muscle. Keywords: Human skeletal muscle time course response to IL-6 infusion IL-6 was infused...
ORGANISM(S): Homo sapiens 
2008-05-27 | E-GEOD-10685 | biostudies-arrayexpress
MetabolomicsIntegration of magnetic resonance imaging and protein and metabolite CSF measurements to enable early diagnosis of secondary progressive multiple sclerosis

Molecular networks in neurological diseases are complex. Despite this fact, contemporary biomarkers are in most cases interpreted in isolation, leading to a significant loss of information and power. We present an analytical approach to scrutinize and combine information from biomarkers originati...

2018-08-13 | MTBLS558 | MetaboLights
ProteomicsEnhancing the chondrogenic potential of chondrogenic progenitor cells by deletion of RAB5C
Osteoarthritis (OA) is the most prevalent chronic joint disease that affects a majority of the elderly. Chondrogenic progenitor cells (CPCs) reside in late stage OA cartilage tissue, producing a fibrocartilagenous extra-cellular matrix and can be manipulated in-vitro, to deposit proteins of healthy ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021785 | Pride
Chondrogenic progenitor cells  rab5c  osteoarthritis 
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