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d-serine is naturally present throughout the human body. It is also used as add-on therapy for treatment-refractory schizophrenia. d-Serine interacts with the strychnine-insensitive glycine binding site of NMDA receptor, and this interaction could lead to potentially toxic activity (i.e., excitotoxi...
ORGANISM(S): Rattus norvegicus 
Genome-wide binding of transcription factors SoxN and D in stage 12-17 wild type embryos (SoxNDam and DDam), of SoxN in D mutants (D-SoxNDam) and of D in SoxN mutants (SoxN-DDam). Four DamID experiments. Three biological replicates per experiment. Two conditions: Dam (control) vs SoxNDam or DDam or ...
ORGANISM(S): Drosophila melanogaster 
Vitamin D is an important calcium-regulating hormone with diverse functions in numerous tissues including the brain. Increasing evidence suggests that vitamin D may play a role in maintaining cognitive function and that vitamin D deficiency may accelerate age-related cognitive decline. Using aging...
ORGANISM(S): Rattus norvegicus 
Aim of the study was to profile and quantify the proteins head region of D. melanogaster that are changing as a result of phytohormone administration. Data-independent acquisition (DIA) bases quantitative proteomics approach were used to achieve this aim. An Orbitrap Fusion Tribrid mass spectrometer...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-05-22 | PXD044924 | Pride
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