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ProteomicsCombinatorial targeting of the miR-379/miR-410 cluster normalizes glucose and lipid homeostasis in diabetes and obesity
Non-coding RNAs from the Dlk1-Dio3 locus are critical for the maturation of metabolic tissues in early stages of postnatal development; however, their role in the mature organs remains elusive. Herein, we show that microRNAs from the miR-379/miR-410 cluster are robustly upregulated in livers of obes...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-30 | PXD044478 | Pride
Liver Microrna Mouse 
UnknownA group B Streptococcus alpha-like protein subunit vaccine induces functionally active antibodies in humans targeting homotypic and heterotypic strains.
Not available
S-EPMC8861819 | biostudies-literature
ProteomicsDepletion of the RNA-binding protein PURA triggers changes in posttranscriptional gene regulation and loss of P-bodies
The RNA-binding protein PURA has been implicated in the rare, monogenetic, neurodevelopmental disorder PURA Syndrome. PURA binds both DNA and RNA and has been associated with various cellular functions. Only little is known about its main cellular functions and the molecular pathways affected upon P...
ORGANISM(S): Homo sapiens (Human) 
2022-12-19 | PXD030266 | Pride
Pura 
UnknownGreenland records of aerosol source and atmospheric lifetime changes from the Eemian to the Holocene.
Not available
S-EPMC5902614 | biostudies-literature
UnknownVentilation strategies and risk factors for intraoperative respiratory critical events and postoperative pulmonary complications in neonates and small infants: a secondary analysis of the NECTARINE cohort<sup>☆</sup>.
Not available
S-EPMC12597469 | biostudies-literature
UnknownGenome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.
Not available
S-EPMC5010513 | biostudies-literature
UnknownMultiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
Not available
S-EPMC3670748 | biostudies-literature
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