Sort   by:  
 Page size 
TranscriptomicsMeHg exposure zebrafish embryos vs control
Gene respons in the central nervous system of zebrafish embryos exposed to the neurotoxicant methyl mercury Two-condition experiment, control vs MeHg exposure embryos (60 µg/l), Biological replicates: 4, dye swaps
ORGANISM(S): Danio rerio 
2012-05-14 | E-GEOD-37970 | biostudies-arrayexpress
ProteomicsMitochondrial stress in GLA mutants Zebrafish is independent of globotriaosylceramide accumulation
Fabry disease (FD) is a hereditary lysosomal storage disorder caused by mutations in GLA gene resulting in reduction or lack of α-galactosidase A activity. In humans, enzymatic deficiency leads to accumulation of globotriaosylceramide (Gb3) and other glycosphingolipids in lysosomes. Current therapie...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2023-10-24 | PXD035409 | Pride
Alpha-galactosidase a/ fabry disease/ lysosome/ mitochondrial activity/ proteomic approach 
GenomicsRNA-sequençing of 21 inflammatory hepatocellular adenomas
The French ICGC project on liver tumors is coordinated by Pr Jessica Zucman-Rossi and funded by Inca (French Institute for Cancer). The aim of the present project is to identify the catalog of somatic and germline mutations in liver tumors.The present series corresponds to 21 RNA-seq of IHCA samples...
EGAS00001003685 | EGA
TranscriptomicsA gp130-induced Src/Yes-YAP Cascade Links Inflammation to Regeneration in the Mammalian Intestine
gp130Act cDNA was PCR-amplified and inserted into a plasmid containing the 12.4-kb Villin promoter. The 15.7-kb expression cassette was excised by PmeI digestion, purified, and injected into fertilized C57BL/6 oocytes to obtain founder mice, two of which transmitted the gp130Act transgene. Small int...
ORGANISM(S): Mus musculus 
2015-02-21 | E-MTAB-2400 | biostudies-arrayexpress
GenomicsWhole Exome Sequencing of 15 Tumor/Normal pairs of inflammatory hepatocellular adenomas
The French ICGC project on liver tumors is coordinated by Pr Jessica Zucman-Rossi and funded by Inca (French Institute for Cancer). The aim of the present project is to identify the catalog of somatic and germline mutations in liver tumors. The present series corresponds to 15 Tumor/Normal pairs of ...
EGAS00001003686 | EGA
MetabolomicsTranscriptomics and Metabolomics Reveal Alterations in Xenobiotic Metabolism and Appearance of Steroidal Alkaloid Metabolites in Mouse Livers after Tomato Consumption

SCOPE: Tomato consumption is associated with many health benefits including lowered risk for developing certain cancers. It is hypothesized that tomato phytochemicals are transported to the liver and other tissues where they alter gene expression in ways that lead to favorable he...

2023-06-13 | MTBLS6715 | MetaboLights
GenomicsFunGeST - Functional Genomics from cancer research to personalized medicine
Data Access Committee EGAC00001002924
EGAC00001002924 | EGA
ProteomicsExtended multiplexing of TMT labeling reveals age and high fat diet specific proteome changes in mouse epididymal adipose tissue
Age-related and/or high caloric intake driven changes in visceral adipose tissue contribute to the development of diabetes and cardiovascular disease. The lack of reliable, high-throughput methods to analyze the adipose tissue protein composition has limited our understanding of the protein network...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2018-07-03 | MSV000082569 | MassIVE
TranscriptomicsProtein affects gene expression and prevents lipid accumulation in the liver in mice
Obesity and associated increased prevalence of non-alcoholic fatty liver (NAFLD) disease is suggested to be positively modulated by a high protein (HP) diet in humans and rodents. The aim was to detect mechanisms by which a HP diet prevents hepatic lipid accumulation by means of transcriptomics. To ...
ORGANISM(S): Mus musculus 
2012-11-21 | E-GEOD-37897 | biostudies-arrayexpress
TranscriptomicsInitial analysis of copy number variations in cattle selected for resistance or susceptibility to intestinal nematodes
Here we describe the initial analysis of copy number variations in cattle selected for resistance or susceptibility to intestinal nematodes The custom aCGH chips that interrogated the whole genome CNVs were build for 3 pairs of contemporary parasite-susceptible and resistant Angus.
ORGANISM(S): Bos taurus 
2010-12-22 | E-GEOD-21538 | biostudies-arrayexpress
Sort   by:  
 Page size