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TranscriptomicsDetection of unbalanced insertions by aCGH and FISH
Insertions occur when a segment of one chromosome is translocated and inserted into a new region of the same chromosome or a non-homologous chromosome. We report 69 cases with unbalanced insertions identified using array CGH and FISH, representing 1.25% of 5,683 cases referred to our laboratory for ...
ORGANISM(S): Homo sapiens 
2011-02-28 | E-GEOD-27080 | biostudies-arrayexpress
TranscriptomicsThe effects of permethrin on the transcriptome of an endangered fish, the delta smelt (Hypomesus transpacificus)
Research on the effects of contaminants on fishes is often conducted on well-studied model test species, whose responses may be different than those of species of conservation concern. We used an oligonucleotide microarray to examine the effects of permethrin, a widely used pyrethroid pesticide, on ...
ORGANISM(S): Hypomesus transpacificus 
2015-09-01 | E-GEOD-67521 | biostudies-arrayexpress
TranscriptomicsLinking transcriptional responses to organismal tolerance reveals mechanisms of thermal sensitivity in a mesothermal endangered fish
We exposed adult delta smelt to varying levels of sublethal thermal stress to quantify the genes involved in their cellular stress response and identify sublethal stress thresholds Fourty-nine samples were run on fourty-nine arrays, with 3-6 replicates for each treatment or control
ORGANISM(S): Hypomesus transpacificus 
2015-08-25 | E-GEOD-67190 | biostudies-arrayexpress
TranscriptomicsSublethal costs of salinity stress contribute to habitat limitation in an endangered estuarine fish
We exposed adult delta smelt to treatments of increased salinities to quantify the transcriptomic responses involved in coping with osmotic stress 70 samples were run on 70 arrays, with 1-4 replicates for each treatment or control
ORGANISM(S): Hypomesus transpacificus 
2015-12-31 | E-GEOD-72772 | biostudies-arrayexpress
ProteomicsTissue architectural cues mediated by integrin signaling
Analysis of human or mouse tumor cell lines that target to different organs upon extravasation
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-06-21 | MSV000084006 | MassIVE
TranscriptomicsAcquired genomic copy number aberrations and survival in chronic lymphocytic leukemia
Genomic aberrations are of predominant importance to the biology and clinical outcome of patients with chronic lymphocytic leukemia (CLL), and FISH-based genomic risk classifications are routinely used in clinical decision making in CLL. One of the known limitations of CLL FISH is the inability to ...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-30777 | biostudies-arrayexpress
TranscriptomicsWhole transcriptomic sequencing of zebrafish rx3 mutants during optic vesicle morphogenesis
To identify genes regulated by Rx3 during optic vesicle morphogenesis, adult zebrafish carriers of a null rx3 mutation were mated. Before 13 hours post fertilization (hpf), the earliest time point at which optic vesicle evagination phenotypes could be reliably detected, offspring were phenotypically...
ORGANISM(S): Danio rerio 
2014-09-30 | E-GEOD-52652 | biostudies-arrayexpress
TranscriptomicsHNRPA2B1 HITS-CLIP
Expression, crosslinking and immunoprecipitation of tagged HNRPA2B1 (variant A2) to identify bound RNA sequences RNA molecules that are immunoprecipitated are sequenced followed purification under denaturing conditions
ORGANISM(S): Homo sapiens 
2012-02-28 | E-GEOD-35799 | biostudies-arrayexpress
TranscriptomicsOlive oil phenols and GE in the aging mouse brain
The aim of this study was to evaluate whether the dietary treatment with olive oil phenols modifies the profile of microRNA and gene expression in different areas of the aging mouse brain and to correlate these changes with the cognitive and motor changes observed in the same aging animals. C57Bl/...
ORGANISM(S): Mus musculus 
2013-09-10 | E-MTAB-1530 | biostudies-arrayexpress
TranscriptomicsFundulus exposed to arsenic as embryos
The present study used microarray expression profiling to determine the effects of embryonic arsenic exposure. Fertilized killifish (Fundulus heteroclitus) eggs were exposed to 0, 5, 15, or 25ppm arsenic as sodium arsenite. To examine differentially expressed genes, the microarrays were probed usi...
ORGANISM(S): Fundulus heteroclitus 
2011-07-31 | E-GEOD-29976 | biostudies-arrayexpress
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