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TranscriptomicsTranscriptional analysis of ypeIR mutation in Yersinia pestis at 37°C
The etiologic agent of bubonic plague, Yersinia pestis, senses cell density-dependent chemical signals to synchronize transcription between cells of the population in a process named quorum sensing. Though the closely related enteric pathogen Y. pseudotuberculosis uses quorum sensing system to regul...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30341 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of Yersinia pestis AHL quorum sensing at 37°C
Quorum sensing is a cell to cell communication process that involves chemical signaling. Yersinia pestis, the agent of plague, has two functional AHL quorum sensing systems Ysp and Ype. For several reasons, it was not clear what effect AHL pathways have on virulence gene expression and survival in t...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30331 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of Yersinia pestis Ype AHL quorum sensing at 30°C
Quorum sensing is a cell to cell communication process that involves chemical signaling. Yersinia pestis, the agent of plague, has two functional AHL quorum sensing systems Ysp and Ype. For several reasons, it was not clear what effect AHL pathways have on virulence gene expression and survival in t...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30332 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of Yersinia pestis Ysp AHL quorum sensing at 37°C
Quorum sensing is a cell to cell communication process that involves chemical signaling. Yersinia pestis, the agent of plague, has two functional AHL quorum sensing systems Ysp and Ype. For several reasons, it was not clear what effect AHL pathways have on virulence gene expression and survival in t...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30328 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of Yersinia pestis Ysp AHL quorum sensing at 30°C
Quorum sensing is a cell to cell communication process that involves chemical signaling. Yersinia pestis, the agent of plague, has two functional AHL quorum sensing systems Ysp and Ype. For several reasons, it was not clear what effect AHL pathways have on virulence gene expression and survival in t...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30329 | biostudies-arrayexpress
TranscriptomicsLuxS/AI-2 quorum sensing microarray comparison in Yersinia pestis at 30°C
The AI-2 quorum-sensing system has been linked to diverse phenotypes and regulatory changes in pathogenic bacteria. In strain CO92, the AI-2 signal is produced in a luxS-dependent manner, reaching maximal levels of 2.5 μM in late logarithmic growth, and both wild type and pigmentation mutant strain...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30108 | biostudies-arrayexpress
Transcriptomics3 quorum sensing signals add in microarray comparison in Yersinia pestis at 30°C
The quorum-sensing system has been linked to diverse phenotypes and regulatory changes in pathogenic bacteria. In strain CO92, the AI-2 signal is produced in a luxS-dependent manner, reaching maximal levels of 2.5 μM in late logarithmic growth, and both wild type and pigmentation mutant strains mad...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30109 | biostudies-arrayexpress
MetabolomicsInsights into Metabolic Changes Caused by the Trichoderma virens-Maize Root Interaction
The interactions of crops with root-colonizing endophytic microorganisms are highly relevant to agriculture, because endophytes can modify plant resistance to pests and increase crop yields. We investigated the interactions between the host plant Zea mays and the endophytic fungus Trichode...
2021-07-08 | MTBLS1964 | MetaboLights
MetabolomicsIntegrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection
The metabolic effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on human blood plasma were characterized using multi-platform metabolic phenotyping with Nuclear Magnetic Resonance (NMR) spectroscopy and liquid chromatography-mass spectrometry (LC-MS). Quantitative mea...
2021-01-29 | MTBLS2014 | MetaboLights
TranscriptomicsTranscriptional analysis of temperature regulation in Yersinia pestis
Temperature is a key environmental factor for facultative pathogens during the host adaptation response. To assess the functional role of temperature in Yersinia pestis, a microarray study was conducted comparing the Δpgm (pigmentation-negative) R88 strain grown at 37°C or 30°C. Six independent R...
ORGANISM(S): Yersinia pestis 
2016-07-03 | E-GEOD-30333 | biostudies-arrayexpress
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