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TranscriptomicsMicroarray of neural progenitor cells from neonatal lung injury mice treated with placebo or umbilical-cord mesenchymal stromal cell extracellular vesicles or untreated, as well as age-matched control mice
The purpose of this experiment was to determine the transcriptional differences between neural progenitor cells from neonatal lung injury mice vs. control mice, as well as neonatal lung injury mice treated with umbilical-cord mesenchymal stromal cell extracellular vesicles vs. neonatal lung injury m...
ORGANISM(S): Mus musculus 
2022-05-17 | E-MTAB-11157 | biostudies-arrayexpress
ProteomicsPreferential phosphorylation on old histones during early mitosis in human cells
How histone posttranslational modifications (PTMs) are inherited through cell cycle remains poorly understood. Canonical histones are made in the S phase of cell cycle. Combining mass spectrometry-based technologies and stable isotope labeling by amino acids in cell culture (SILAC), we interrogate t...
ORGANISM(S): Homo sapiens (Human) 
2016-06-01 | PXD003709 | Pride
Mass spectrometry Mitosis Histone modifications Cell cycle Histone phosphorylation 
TranscriptomicsSingle-cell transcriptome profiling of Sox2-low iPS cells
Single-cell RNA-seq was performed on homozygous Sox2 knockout induced pluripotent stem (iPS) cells, where residual Sox2 expression is observed from incompletely silenced retroviral transgenes. These were compared to Sox2-low iPS cells rescued by exogenous Sox2 transgenic expression, and wild-type iP...
ORGANISM(S): Mus musculus 
2020-12-28 | E-MTAB-9931 | biostudies-arrayexpress
TranscriptomicsWhy nicotine is BAD for your Fallopian tube: an explanation for the association between smoking and ectopic pregnancy
Why nicotine is BAD for your Fallopian tube: an explanation for the association between smoking and ectopic pregnancy
ORGANISM(S): Homo sapiens 
2014-08-01 | E-MTAB-1290 | biostudies-arrayexpress
UnknownDevelopment of a Personalized Visualization and Analysis Tool to Improve Clinical Care in Complex Multisystem Diseases With Application to Scleroderma.
Not available
S-EPMC12919693 | biostudies-literature
TranscriptomicsPotential link between biotic defense activation and recalcitrance to induction of somatic embryogenesis in shoot primordia from adult trees of white spruce (Picea glauca)
The goal is to examine the molecular aspects underpinning somatic embryogenesis (SE) within shoot tissues of adult white spruce trees by conducting transcriptome-wide expression profiling of shoot explants taken from responsive and nonresponsive genotypes. One-color analysis of vegetative buds in so...
ORGANISM(S): Picea glauca 
2013-10-17 | E-GEOD-46977 | biostudies-arrayexpress
TranscriptomicsExpression data from mice on a high fat, high carbohydrate diet treated with exenatide
The present study was constructed to confirm previous findings that mice on a high fat diet (HFD) treated by subcutaneous injection with exenatide (EXE) at 3µg/kg once daily for 6 weeks develop exocrine pancreatic injury (Rouse et al. 2014). The present study included 12 weeks of EXE exposure at mu...
ORGANISM(S): Mus musculus 
2014-06-01 | E-GEOD-54774 | biostudies-arrayexpress
TranscriptomicsA gene regulatory network for neural induction
During early vertebrate development, signals from a special region of the embryo, the organizer, can re-direct the fate of non-neural ectoderm cells to form a complete, patterned nervous system. The process has generally been imagined as the result of a single signaling event, causing a simple switc...
ORGANISM(S): Gallus gallus 
2023-03-14 | E-MTAB-10408 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse embryonic stem cells with knockout of Nhlrc2 gene or addition of FINCA disease causing NHLRC2 p.Asp148Tyr variant
Fibrosis, neurodegeneration, and cerebral angiomatosis (FINCA) (OMIM 618278) is a rare infantile-onset disease caused by variants in NHL repeat containing 2 (NHLRC2) gene. NHLRC2 is essential for mouse gastrulation (Hiltunen et al., 2022). Here, RNA sequencing was performed on four wild type (WT), f...
ORGANISM(S): Mus musculus 
2025-05-22 | E-MTAB-14174 | biostudies-arrayexpress
TranscriptomicscDNA microarray expression data of heart, skeletal muscle and liver comparing Irf2bp2-null mice to wild type controls
Interferon regulatory factor 2 binding protein 2 (Irf2bp2), a co-repressor of Irf2, is required for fetal hepatic erythropoiesis through the expansion of erythromyeloid progenitors. Mice with germline ablation of the entire Irf2bp2 transcript produced no viable Irf2bp2-null (knockout, KO) pups in fi...
ORGANISM(S): Mus musculus 
2023-02-02 | E-MTAB-11558 | biostudies-arrayexpress
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