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MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine and human plasma quantitative L-arginine and methylarginines UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS685 | MetaboLights
MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine kidney and plasma UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS680 | MetaboLights
GenomicsICGC Oesophageal Adenocarcinoma sequence data - fc_paper_dna_release - samples
Data supporting: "Patient-specific detection of cancer genes reveals recurrently perturbed processes in esophageal adenocarcinoma." Mourikis et al. WGS (BAM files) 521 samples
EGAD00001004775 | EGA
MetabolomicsA Pilot Characterization of the Human Chronobiome
Physiological function, disease expression and drug effects vary by time-of-day. Clock disruption in mice results in cardio-metabolic, immunological and neurological dysfunction; circadian misalignment using forced desynchrony increases cardiovascular risk factors in humans. Here we integrated data ...
2018-05-16 | MTBLS656 | MetaboLights
GenomicsICGC Oesophageal Adenocarcinoma sequence data - TLR_pathway_study - samples
upcoming publication
EGAD00001001960 | EGA
GenomicsICGC Oesophageal Adenocarcinoma sequence data - dcc_release_28 - samples
WGS sequencing for 409 cases (832 samples) from the ICGC ESAD-UK project Tumours 50x Normals 30x HiSeq X BAM files These samples are all available in ICGC release 28
EGAD00001004137 | EGA
GenomicsICGC Oesophageal Adenocarcinoma sequence data - 100_all_samples - samples
All samples from the "100" project
EGAD00001001457 | EGA
GenomicsICGC Oesophageal Adenocarcinoma sequence data - 129_cohort - samples
Sequencing data for ICGC Oesophageal Adenocarcinoma tissue samples - 129_cohort EAC whole genomic sequencing data - Publication Secrier & Li et al., 2016, Nature Genetics
EGAD00001002218 | EGA
GenomicsICGC Oesophageal Adenocarcinoma sequence data - 100 - samples
Samples from the "100" project that are in the ICGC PanCancer project.
EGAD00001001071 | EGA
GenomicsICGC Oesophageal Adenocarcinoma sequence data - mobile_elements - samples
Samples from Edwards et al 2015 - doi:10.1186/s12864-015-1685-z
EGAD00001001048 | EGA
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