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OBJECTIVES: This study used hydrogen nuclear magnetic resonance spectroscopy (1H NMR) for the first-time to examine differences in the metabolomic profile of stifle joint synovial fluid from dogs with cranial cruciate ligament rupture with and without meniscal injuries, in order ...

2025-08-14 | MTBLS6050 | MetaboLights
Recent advances in genome technologies have uncovered thousands of long non-coding RNAs (lncRNAs) whose function in the immune system has been largely unexplored. Members of the Toll-like receptor (TLR) family activate an inducible program of inflammatory genes important in host defenses. Here we p...
ORGANISM(S): Mus musculus 
Patients received standardized coartem therapy. Briefly, each pill contains 20 mg of artemether and 120 mg of lumefantrine. The dose and total coarse of tablets is based on the patients body weight. Blood was drawn from patients prior to anti-malarial treatment (day 0) and after treatment (day42 for...
ORGANISM(S): Homo sapiens 
C57BL/6 mice were maintained in specific pathogen-free conditions in accordance with the Institutional Animal Care and Use Committee. Listeria monocytogenes (clinical isolate 10403s) was from V. Boyartchuk (NTNU, Trondheim, Norway) and infected as previously described (PMID 24477914) for 24 hours be...
ORGANISM(S): Mus musculus domesticus 
Investigation of RNA transcript abundance in aortic tissue of BMAL-/- versus BMAL+/+ control mice at ZT14 Experiment Overall Design: One-way ANOVA design with Strain (BMAL-/- versus BMAL+/+) as the independent variable. Control group has five biological replicates, BMAL-/- group has four biological ...
ORGANISM(S): Mus musculus 
Investigation of RNA transcript abundance in aortic tissue of NPAS2 mutant versus wild type mice at ZT14 Experiment Overall Design: One-way ANOVA design with Strain (NPAS mutant/WT) as the independent variable and five replicates in each group
ORGANISM(S): Mus musculus 
For patients with triple negative breast tumours (TNBCs), lacking receptors for oestrogen, progesterone or HER2 on their cell surface, chemotherapy is the main treatment. The taxanes, paclitaxel (PTX) and docetaxel, have become the most commonly-used chemotherapies for these kinds of breast cancer....
ORGANISM(S): Homo sapiens 
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