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TranscriptomicsTranscriptional profile of PBMCs in patients with acute RSV or Influenza infection
To study the transcriptional profile of patients with acute RSV or Influenza infection,children of median age 2.4 months (range 1.5-8.6) hospitalized with acute RSV and influenza virus infection were offered study enrollment after microbiologic confirmation of the diagnosis. Blood samples were coll...
ORGANISM(S): Homo sapiens 
2012-03-12 | E-GEOD-34205 | biostudies-arrayexpress
TranscriptomicsTrivalent Inactivated Influenza Vaccine (TIV) and Live Attenuated Influenza Vaccine (LAIV) Induce Different B cell and Transcriptional Responses in Children
LAIV and TIV are effective for prevention of influenza infection in children, but the mechanisms associated with protection are still not well defined. We analyzed the differences in B cell responses and transcriptional profiles. Compared to baseline, LAIV elicited a significant increase in naM-CM-/...
ORGANISM(S): Homo sapiens 
2014-03-31 | E-GEOD-52005 | biostudies-arrayexpress
TranscriptomicsThe response of human primary airway epithelial cells to Influenza or RSV infection [hAECs_Illumina]
To investigate how human airway epithelial cells respond to Influenza or RSV infection, we harvested airway epithelial cells from the mainstream bronchi of human donors and cultured them as previously described (Pickles et al,1998) in a polarized system that resembles the in vivo mucociliary pseudo...
ORGANISM(S): Homo sapiens 
2012-03-12 | E-GEOD-32139 | biostudies-arrayexpress
TranscriptomicsThe response of human primary airway epithelial cells to Influenza or RSV infection [hAECs_Agilent].
To investigate how human airway epithelial cells respond to Influenza or RSV infection, we harvested airway epithelial cells from the mainstream bronchi of human donors and cultured them as previously described (Pickles et al,1998) in a polarized system that resembles the in vivo mucociliary pseudo...
ORGANISM(S): Homo sapiens 
2012-03-12 | E-GEOD-32138 | biostudies-arrayexpress
TranscriptomicsThe response of murine primary airway epithelial cells to Influenza infection and the importance of Interferon type I signaling in this response [mAEC].
To investigate how murine airway epithelial cells respond to Influenza infection and how important interferon type I signaling is for this response, we harvested airway epithelial cells from the tracheas of wild type, interferon type I knockout(IFNaR-/-) and STAT1 knockout (STAT1-/-) mice and cultur...
ORGANISM(S): Mus musculus 
2012-03-12 | E-GEOD-32137 | biostudies-arrayexpress
TranscriptomicsThe response of PBMCs and primary airway epithelial cells to Influenza and RSV virus
This SuperSeries is composed of the following subset Series: GSE32137: The response of murine primary airway epithelial cells to Influenza infection and the importance of Interferon type I signaling in this response [mAEC]. GSE32138: The response of human primary airway epithelial cells to Influenza...
ORGANISM(S): Homo sapiens 
2012-03-12 | E-GEOD-32140 | biostudies-arrayexpress
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