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TranscriptomicsMicroarray data of foetal liver Lin- cKit+ cells obtained from Fh1-deficient and control 14.5 dpc mouse embryos
Haematopoiesis-specific Fh1 deletion causes lethal foetal liver haematopoietic defects. To understand the impact of Fh1 deletion on the transcriptome of foetal liver Lin- c-Kit+ cells we preformed microarray analysis. To conditionally delete Fh1 in the foetal liver we used the Vav-iCre recombinase a...
ORGANISM(S): Mus musculus 
2017-02-08 | E-MTAB-5425 | biostudies-arrayexpress
TranscriptomicsMicroRNA Expression profiles of mature hepatocytes and foetal liver progenitor cells
Human liver progenitor cells (LPCs) show therapeutic potential, however, their in vitro culture results in inadequate function and phenotypic instability reflecting incomplete understanding of in vivo processes. Foetal LPCs capable of differentiation to a hepatocyte phenotype were isolated and mRNA ...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-57833 | biostudies-arrayexpress
TranscriptomicsMultiome scRNA- and scATAC-seq of healthy and trisomy 21 (Down's syndrome) foetal liver
Here, we performed multiome sequencing (snRNA-seq + snATAC-seq) of human fetal liver samples from 3 trisomy 21 (Ts21) and 3 healthy foetuses (median age 14 post-conception weeks). The data set is composed of approximately 60,000 CD45+ foetal liver cells.
ORGANISM(S): Homo sapiens 
2024-07-17 | E-MTAB-13070 | biostudies-arrayexpress
GenomicsSingle cell atlas of the mouse foetal liver
Single cell atlas of the mouse foetal liver
PRJNA746333 | ENA
UnknownSingle cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors.
Not available
S-EPMC6659636 | biostudies-literature
GenomicsMultiome scRNA- and scATAC-seq of healthy and trisomy 21 (Down's syndrome) foetal liver
Multiome scRNA- and scATAC-seq of healthy and trisomy 21 (Down's syndrome) foetal liver
PRJEB63257 | ENA
GenomicsSpatial transcriptomics (10x Visium) of healthy and trisomy 21 (Down's syndrome) foetal liver
Spatial transcriptomics (10x Visium) of healthy and trisomy 21 (Down's syndrome) foetal liver
PRJEB63155 | ENA
ProteomicsFoetal and adult HSPCs - Comprehensive Proteomic Characterization of Ontogenic Changes in Hematopoietic Stem and Progenitor Cells
Haematopoietic stem and progenitor cells (HSPCs) in the foetus and adult possess distinct molecular landscapes that regulate cell fate and change their susceptibility to initiation and progression of haematopoietic malignancies. The proteomic programs that govern these differences remain elusive. In...
ORGANISM(S): Mus musculus (Mouse) 
2017-12-12 | PXD006876 | Pride
Haematopoiesis Mouse Adult bone marrow Foetal liver 
GenomicsMicroRNA Expression profiles of mature hepatocytes and foetal liver progenitor cells
Human liver progenitor cells (LPCs) show therapeutic potential, however, their in vitro culture results in inadequate function and phenotypic instability reflecting incomplete understanding of in vivo processes. Foetal LPCs capable of differentiation to a hepatocyte phenotype were isolated and mRNA ...
ORGANISM(S): Rattus norvegicus Mus musculus Homo sapiens 
2015-05-01 | GSE57833 | GEO
TranscriptomicsAffymetrix profile of human liver progenitor cells
Human liver progenitor cells (LPCs) show therapeutic potential, however, their in vitro culture results in inadequate function and phenotypic instability reflecting incomplete understanding of in vivo processes. Foetal LPCs capable of differentiation to a hepatocyte phenotype were isolated and mRNA ...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-57812 | biostudies-arrayexpress
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