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MetabolomicsA Multi-Omic View of Host-Pathogen-Commensal Interplay in Salmonella-Mediated Intestinal Infection
The potential for commensal microorganisms indigenous to a host (the microbiome or microbiota) to alter infection outcome by influencing host-pathogen interplay is largely unknown. We used a multi-omics systems approach, incorporating proteomics, metabolomics, glycomics, and metagenomics, to explore...
2014-06-24 | MTBLS96 | MetaboLights
MetabolomicsFood Deprivation Enhances Disease Resistance: Underlying Mechanisms in Oysters Confronted with Pacific Oyster Mortality Syndrome

Variation in food availability can shape host susceptibility and pathogen virulence, thereby impacting disease outcomes. An ad libitum diet may enhance host physiology and immunity but it can also favor pathogen proliferation. Here, we investigated how food availability (ad libitum vs. starvation...

2025-11-14 | MTBLS13313 | MetaboLights
MetabolomicsComparing Campylobacter jejuni to three other enteric pathogens in OligoMM 12 mice reveals pathogen-specific host and microbiota responses
Campylobacter jejuni, non-typhoidal Salmonella spp., Listeria monocytogenes and enteropathogenic/enterohemorrhagic Escherichia coli (EPEC/EHEC) are leading causes of food-borne illness worldwide. Citrobacter rodentium has been used to model EPEC and EHEC infection ...
2025-02-25 | MTBLS11078 | MetaboLights
MetabolomicsAntimicrobial Efficacy of Bifidobacterium longum FB1-4 Cell-Free Supernatant Against MRSA: Insights into Mechanisms and Food Matrix Application

The food safety landscape faces a significant challenge from methicillin-resistant Staphylococcus aureus (MRSA), a virulent and antibiotic-resistant foodborne pathogen. This study investigates the antimicrobial properties and mechanisms of cell-free supernatant (CFS) from Bifidobacterium longum F...

2026-02-26 | MTBLS13481 | MetaboLights
MetabolomicsTitanium dioxide in food induces sex- and microbiota-dependent metabolic disorders, and worsens high-fat diet outcomes
Ultra-processed food consumption has been linked to the rising global burden of metabolic diseases, but the specific contribution of additives commonly used in these products remains unclear. Given the bactericidal properties of the food-grade (fg) additive titanium dioxide (TiO2) and the key role o...
2026-05-19 | MTBLS14529 | MetaboLights
MetabolomicsTransgenic Tobacco Plants Expressing Synthetic Peptides: A Functional and Structural Analysis for Pathogen Resistance
The emergence of multidrug-resistant pathogens poses a significant threat to human health and agriculture. Current antimicrobial strategies against phytopathogens are often ineffective, failing to ensure food security while contributing to environmental pollution. Synthetic antimicrobial peptides (A...
2025-09-25 | MTBLS12255 | MetaboLights
Genomics100K Food Pathogen Project
100K Food Pathogen Project
PRJNA186441 | ENA
MetabolomicsProtection of gut microbiota-fermented 2'-fucosyllactose against Campylobacter jejuni through microbial metabolites-enteric pathogen crosstalk

Untargeted metabolomics was performed to characterize the metabolite profiles of fecal fermentation supernatants. Human fecal inoculum was incubated anaerobically with FL (10 mg/mL) or without any carbohydrate for 36 h. After centrifugation, the resulting supernatants were collected and analyzed....

2026-06-16 | MTBLS14485 | MetaboLights
GenomicsFood and Drug Administration, Center for Food Safety and Applied Nutrition: FoodBorne Pathogen Research
Food and Drug Administration, Center for Food Safety and Applied Nutrition: FoodBorne Pathogen Research
PRJNA186875 | ENA
Unknown100K Pathogen Genome Project: 306 Listeria Draft Genome Sequences for Food Safety and Public Health.
Not available
S-EPMC5331488 | biostudies-literature
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