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Polymeric elastomers are extensively employed to fabricate implants intended for prolonged implantation. However, implantation of the elastomers can induce strong immune rejection reaction known as foreign body response (FBR), resulting in the rejection of foreign implants and thereby diminishing th...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD054629 | Pride
This study dermined the temporal gene expression profile of myeloid subpopulations recruited to the peritoneal cavity to encapsulate implanted foreign material. Sterile foreign objects were inserted into the peritoneal cavities of MacGreen mice (in which the Csf1r promoter directs myeloid-specific ...
ORGANISM(S): Mus musculus 
Foreign body reaction is one of the most important limiting factors to the clinical translation of implantable bioelectronics. The experiment compares the process of foreign body reaction, following the implantation of a silicon device in a mouse peripheral nerve, to that of peripheral nerve injury,...
ORGANISM(S): Mus musculus 
Engineered cytokine-secreting cells to prevent foreign body response against implants
Immunocompatible Elastomer with increased resistance to the foreign body response
Single-cell Analysis of Surface Topography-induced Foreign Body Response to Silicone Implants
Osteopontin Reduces Foreign Body Response in Silicone-Based Implants in Humans and Mice
Allometric tissue-scale forces activate mechanoresponsive immune cells to determine pathological foreign body response to biomedical implants
Role of Macrophages in the Foreign Body Response to Poly(ethylene glycol) Hydrogels
Allometric tissue-scale forces at the implant-tissue interface drive pathological foreign body response.
ORGANISM(S): Mus musculus 
2023-06-05 | GSE227908 | GEO
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