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ProteomicsConserved hydrophilic checkpoints tune FocA-1 mediated formate:H+ symport
FocA belongs to the widespread, evolutionarily ancient formate-nitrite transporter 30 (FNT) family of pentameric anion channels and translocates formic acid bidirectionally. 31 Here, we identify compartmentalized polarity distribution across the complete FocA 32 pore structure – resolved at 2.56 Å –...
ORGANISM(S): Escherichia coli 
2025-11-10 | PXD054538 | Pride
Foca Xlms Cryo em Formate-nitrite transporter 
UnknownMechanism of formate-nitrite transporters by dielectric shift of substrate acidity.
Not available
S-EPMC5376963 | biostudies-literature
UnknownEnergetics and mechanism of anion permeation across formate-nitrite transporters.
Not available
S-EPMC5607303 | biostudies-literature
UnknownMutational widening of constrictions in a formate-nitrite/H+ transporter enables aquaporin-like water permeability and proton conductance.
Not available
S-EPMC8749060 | biostudies-literature
UnknownIs the E. coli Homolog of the Formate/Nitrite Transporter Family an Anion Channel? A Computational Study.
Not available
S-EPMC7037574 | biostudies-literature
UnknownFormate-nitrite transporters carrying nonprotonatable amide amino acids instead of a central histidine maintain pH-dependent transport.
Not available
S-EPMC6333897 | biostudies-literature
UnknownFunctional Characterization of the FNT Family Nitrite Transporter of Marine Picocyanobacteria.
Not available
S-EPMC4390861 | biostudies-literature
UnknownIdentifying the major lactate transporter of Toxoplasma gondii tachyzoites.
Not available
S-EPMC7991638 | biostudies-literature
UnknownDiscovery and Development of Inhibitors of the Plasmodial FNT-Type Lactate Transporter as Novel Antimalarials.
Not available
S-EPMC8624176 | biostudies-literature
UnknownStructural basis of transport and inhibition of the Plasmodium falciparum transporter PfFNT.
Not available
S-EPMC7926216 | biostudies-literature
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