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TranscriptomicsInhibition of MYCN by a PNA anti-gene in alveolar rhabdomyosarcoma
The objective was to identify the molecular mechanisms responsible for in vitro and in vivo efficacy of an anti-MYCN peptide nucleic acid on a preclinical model of alveolar rhabdomyosarcoma. Cells treated with a anti-MYCN PNA exhibit growth arrest and apoptosis, and in vivo tumor growth is blocked. ...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-7959 | biostudies-arrayexpress
TranscriptomicsCopy number data from GIST with KIT mutation
In addition to KIT and PDGFRA mutations, sequential accumulation of other genetic events is involved in the development and progression of gastrointestinal stromal tumors (GISTs). Until recently, the significance of these other alterations has not been thoroughly investigated. The combination of gen...
ORGANISM(S): Homo sapiens 
2010-08-27 | E-GEOD-20709 | biostudies-arrayexpress
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