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TranscriptomicsOverlapping DNA methylation dynamics in mouse intestinal cell differentiation and early stages of malignant progression
Mouse models of intestinal crypt cell differentiation and tumorigenesis have been used to characterize the molecular mechanisms underlying both processes. DNA methylation is a key epigenetic mark and plays an important role in cell identity and differentiation programs and cancer. To get insights i...
ORGANISM(S): Mus musculus 
2014-09-11 | E-GEOD-61318 | biostudies-arrayexpress
TranscriptomicsChanges in the Pattern of DNA Methylation Associate with Twin Discordance in SLE
This is the first high-throughput analysis of DNA methylation in autoimmune diseases. We have used a cohort of MZ twins discordant for three diseases whose clinical signs often overlap: systemic lupus erythematosus (SLE), rheumatoid arthritis and dermatomyositis. Only MZ twins discordant for SLE fea...
ORGANISM(S): Homo sapiens 
2009-11-16 | E-GEOD-19033 | biostudies-arrayexpress
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