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Alpibectir potentiates the activity of ethionamide and prothionamide, which are second-line antibiotics used for tuberculosis treatment. Both are prodrugs whose antibacterial activity depends on bioactivation by oxidases, including the Baeyer-Villiger monooxygenase MymA. Alpibectir binds the transcr...
ORGANISM(S): Mycobacterium tuberculosis 
RNA expression in immortalized lymphocytes of schizophrenia and bipolar disorders patients were compared to that of their non-affected relatives to identify genes showing significant differences in expression. The study subjects were recruited in the Eastern Quebec kindred study.
ORGANISM(S): Homo sapiens 
We report the results of a study in which we sought to identify the patients at risk of relapse by using a transcriptomic approach and to clarify the molecular abnormalities that define tumors at risk of relapse. We used pangenomic oligoarrays (Agilent) and hybridized primary tumor with relapse vers...
ORGANISM(S): Homo sapiens 
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