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TranscriptomicsTranscription profiling of xenografted tumors derived from human ovarian cell line model A2780 and its cisplatin resistant variant A2780cis
Molecular mechanisms underlying the development of resistance to platinum treatment in patients with ovarian cancer remain poorly understood. This is mainly due to the lack of appropriate in vivo models allowing identification of factors that are regulated during initial treatment and of acquired re...
ORGANISM(S): Homo sapiens 
2013-10-01 | E-MTAB-1858 | biostudies-arrayexpress
GenomicsFunctional dissection of QTL-region affecting fat-deposition
Functional dissection of QTL-region affecting fat-deposition
ORGANISM(S): Sus scrofa 
2018-10-15 | E-MTAB-1434 | biostudies-arrayexpress
GenomicsActivation of the Integrated Stress Response by a Jumonji Histone Demethylase Inhibitor Induces Pro-Apoptotic Metabolic Reprogramming in Multiple Myeloma
Regulation of gene expression by chromatin modification through methylation of histone lysine residues is a dynamic, reversible process that when deregulated is associated with cancer development. In multiple myeloma, combined inhibition of the histone demethylases JARID1B, UTX and JmjD3 by the smal...
ORGANISM(S): Homo sapiens 
2015-08-21 | E-GEOD-60626 | biostudies-arrayexpress
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