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TranscriptomicsThe FoxO signature in protein breakdown
Under stress conditions mammalian cells activate compensatory mechanisms to survive and maintain cellular function. During catabolic conditions, such as low nutrients, systemic inflammation, cancer or infections, protein breakdown is enhanced and aminoacids are released from muscles to sustain liver...
ORGANISM(S): Mus musculus 
2015-04-24 | E-GEOD-52667 | biostudies-arrayexpress
TranscriptomicsFoxl1-Cre-marked Adult Hepatic Progenitors Have Clonogenic and Bi-Lineage Differentiation Potential - Time Course
The winged helix transcription factor Foxl1 is a marker for progenitor cells and their descendants in the mouse liver in vivo. Here, we purify progenitor cells from Foxl1-Cre; RosaYFP mice and evaluate their proliferative and differentiation potential in vitro. Treatment of Foxl1-Cre; RosaYFP mice w...
ORGANISM(S): Mus musculus 
2011-05-01 | E-GEOD-28890 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic fibroblasts Cre infected vs. control Vector infected
To examine the transcriptional changes that occur following alpha4 deletion, RNA microarray analysis was performed using RNA from alpha4-floxed MEFs 48 hours after infection with the Cre-containing or Vector control virus.
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-1708 | biostudies-arrayexpress
UnknownComputational modeling of ovarian cancer dynamics suggests optimal strategies for therapy and screening.
Not available
S-EPMC8237655 | biostudies-literature
TranscriptomicsExpression of MERTK based on Multiple Sclerosis (MS) risk haplotype
Whole transcriptome RNA-seq analysis to measure group-wise RNA expression level of the MERTK gene in 3 healthy controls (known to be homozygous non-risk haplotype at MERTK gene locus) and to compare this to the group-wise RNA expression level of the MERTK gene in 5 Multiple Sclerosis-affected (MS-af...
ORGANISM(S): Homo sapiens 
2016-02-06 | E-GEOD-77598 | biostudies-arrayexpress
UnknownPerspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st-3rd, 2022-Naples, Italy).
Not available
S-EPMC10375730 | biostudies-literature
TranscriptomicsCholesterol lowering depletes smooth muscle cell-derived fibromyocytes and chondromyocytes from atherosclerotic lesions
Study of the effect of low-density lipoprotein (LDL)-lowering therapies on the heterogeneous population of proliferating smooth muscle cells (SMCs) derived from atherosclerotic plaques in an atherosclerotic mouse model by inducing hypercholesterolemia followed by high or low fat diet.
ORGANISM(S): Mus musculus 
2023-12-08 | E-MTAB-12019 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of maternal serum of women at high-risk of spontaneous preterm birth using NMR and MGWAS approach
Preterm birth (PTB) is a leading global cause of infant mortality. Risk factors include genetics, lifestyle choices and infection. Understanding the mechanism of PTB could aid the development of novel approaches to prevent PTB. This study aimed to investigate the metabolic biomarkers of PTB in early...
2023-05-24 | MTBLS1990 | MetaboLights
UnknownCarboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study.
Not available
S-EPMC6886237 | biostudies-literature
UnknownADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry.
Not available
S-EPMC3252425 | biostudies-literature
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