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TranscriptomicsExpression profile of human lymphatic endothelial cells under static or oscillatory shear stress conditions in the presence or absence of FOXC2
Lymphatic valves are specialized units regularly distributed along collecting vessels that allow unidirectional forward propulsion of the lymph, and its efficient transport from tissues to the bloodstream. Lymphatic endothelial cells that cover lymphatic valve sinuses are subjected to complex flow p...
ORGANISM(S): Homo sapiens 
2015-11-09 | E-GEOD-60152 | biostudies-arrayexpress
TranscriptomicsChIP-chip study aimed at the identification of the repertoire of FOXC2 binding sites affected by the loss of FOXC2 phosphorylation in primary human lymphatic endothelial cells (LECs)
Chromatin immunoprecipitation microarray (ChIP-chip) study using anti-Myc (9E10) antibodies and primary human lymphatic endothelial cells (LECs) transduced with recombinant adenoviruses expressing wild type or phosphorylation-deficient Myc-tagged FOXC2.
ORGANISM(S): Homo sapiens 
2013-07-13 | E-MTAB-596 | biostudies-arrayexpress
TranscriptomicsExpression analysis of colorectal cancer cell line SW480 expressing FOXC2
Investigation of whole genome gene expression level changes in a colorectal cancer cell line SW480 expressing FOXC2, compared to the pBabe control cells. Genes associated with metastasis regulated by FOXC2 in colorectal cancer were analysed. The role of FOXC2 in breast cancer metastasis are furthe...
ORGANISM(S): Homo sapiens 
2014-07-02 | E-GEOD-58980 | biostudies-arrayexpress
TranscriptomicsHMLER cells expressing either FOXC2 or a vector control
We used microarrays to investigate the transcription profile of FOXC2 expression in a human mammary epithelial cell line. HMLER cells were infected with either a control vector or a retroviral vector expressing FOXC2.
ORGANISM(S): Homo sapiens 
2013-02-15 | E-GEOD-44335 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of white adipose tissue of transgenic mice overexpressing the FOXC2 gene compared with adipose tissue of wild type mice
Transcript profiling to identify genes where the mRNA expression levels are differentially regulated in white adipose tissue of transgenic mice overexpressing the FOXC2 gene compared with adipose tissue of wild-type mice.
ORGANISM(S): Mus musculus 
2007-04-25 | E-MEXP-410 | biostudies-arrayexpress
GenomicsFOXC2 knockdown in MDA-MB-231 cells
FOXC2 knockdown in MDA-MB-231 cells
PRJNA971226 | ENA
GenomicsFOXC2-HIS122 and pH-dependent gene expression
FOXC2-HIS122 and pH-dependent gene expression
PRJNA1125484 | ENA
GenomicsFoxc1 and Foxc2 are necessary to maintain glomerular podocytes
Foxc1 and Foxc2 are necessary to maintain glomerular podocytes
PRJNA482531 | ENA
GenomicsFOXC2 and WT1 regulate transcriptional reprogramming during the podocyte response to injury
FOXC2 and WT1 regulate transcriptional reprogramming during the podocyte response to injury
PRJNA879448 | ENA
TranscriptomicsFoxc1 and Foxc2 are necessary to maintain glomerular podocytes
Foxc1 and Foxc2 are highly expressed in adult podocytes. To bypass embryonic lethality of Foxc1 and Foxc2 KO, mice ubiquitously expressing inducible-Cre (ROSA26-CreERT2) were mated with floxed-Foxc1 and floxed-Foxc2 mice. We used microarrays to detail effects of deletions of Foxc1 and Foxc2 on podoc...
ORGANISM(S): Mus musculus 
2018-07-25 | GSE117571 | GEO
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