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MetabolomicsFOXK1 and FOXK2 Promote Cardiomyocyte Proliferation and Heart Regeneration
Promoting the proliferation of endogenous cardiomyocytes represents a promising strategy for treating cardiac injuries. Identifying key factors that regulate cardiomyocyte proliferation can advance the development of novel therapies for heart regeneration. Here we identify that FOXK1 and FOXK2 act a...
2025-02-13 | MTBLS12191 | MetaboLights
GenomicsFOXK2 ChIP-seq
Chromatin immunoprecipitation of FOXK2 (tagged with Flag and His tags) in U2OS cells detected by SOLiD sequencing. ***Correction March 2014: The sample “FOXK2_Dox_treated” has been renamed, it was originally named “FOXK2_rep2”. A new sample “FOXK2_rep2” has been added, with new files. It has come to...
ORGANISM(S): Homo sapiens 
2011-01-20 | E-MTAB-565 | biostudies-arrayexpress
TranscriptomicsFOXK2 promotes AP-1 mediated transcriptional regulation - transcription profiling FOXK2 induction
Transcription profiling of FOXK2 expression in HeLa cells from a stably integrated doxycyline-inducible EGFP-FOXK2 expression construct.
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3040 | biostudies-arrayexpress
TranscriptomicsFOXK2 ChIP-chip
Chromatin immunoprecipitation of FOXK2 (tagged with Flag and His tags) in U2OS cells detected by Affymetrix human promoter array 1.0R.
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3116 | biostudies-arrayexpress
GenomicsFOXK2 ChIP-seq Illumina
Chromatin immunoprecipitation of FOXK2 (tagged with Flag and His tags) in U2OS cells detected by Illumina sequencing
ORGANISM(S): Homo sapiens 
2014-07-23 | E-MTAB-2204 | biostudies-arrayexpress
TranscriptomicsExpression profiling of FOXK2 depletion by siRNA
Expression profiling was done of FOXK2 depletion by siRNA transfection. This was done on the human osteosarcoma U2OS cell line (which stably expresses FOXK2).
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3106 | biostudies-arrayexpress
ProteomicsFOXK2 targeting by the SCF-E3 ligase subunit FBXO24 for ubiquitin mediated degradation modulates mitochondrial respiration
FOXK2 is a crucial transcription factor implicated in a wide array of biological activities and yet understanding of its molecular regulation at the level of protein turnover is limited. Here we identify that FOXK2 is sensitive to degradation by the virulent pathogens P. aeruginosa and K. pneumoniae...
ORGANISM(S): Homo sapiens (Human) 
2024-07-03 | PXD050221 | Pride
Pulldown Foxk2 Lc-ms/ms 
TranscriptomicsExpression profiling of exposure to phorbol myristate acetate - PMA and FOXK2 depletion with siRNA
Expression profiling was done of exposure to phorbol myristate acetate -PMA and FOXK2 depletion by siRNA transfection. This was done on the human osteosarcoma U2OS cell line which stably expresses FOXK2. PMA is an inducer of AP1 activity.
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3107 | biostudies-arrayexpress
ProteomicsA ROS-mediated Oxidation-O-GlcNAcylation cascade governs ferroptosis
Reactive oxygen species (ROS) play a crucial role in lipid peroxidation and the initiation of ferroptosis, significantly affecting chemotherapeutic drug resistance. However, the mechanisms by which ROS function and are sensed remain poorly understood. In this study, we identified O-GlcNAc transferas...
ORGANISM(S): Homo sapiens (Human) 
2025-05-28 | PXD064117 | Pride
Human Ogt Foxk2 Lc-ms/ms 
GenomicsFOXK2 ChIP-seq
FOXK2 ChIP-seq
PRJEB2447 | ENA
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