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TranscriptomicsTranscription profiling of mouse Il10-/- mutants treated with dietary eicosapentaenoic acid (EPA) to investigate intestinal inflammation
Dietary n-3 polyunsaturated fatty acids can reduce inflammation via a range of mechanisms. This study tested the effect of dietary eicosapentaenoic acid (EPA) on intestinal inflammation using interleukin-10 gene-deficient (Il10-/-) mice. Methods: At 35 days of age, 12 weaned Il10-/- and 12 C57 mice ...
ORGANISM(S): Mus musculus 
2008-10-21 | E-GEOD-12028 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse colon from interleukin-10 gene-deficient mice
A total of 30 male IL10-/- (B6.129P2-Il10/J) and 30 male C57 control (C57BL/6J) mice were obtained from The Jackson Laboratory (Bar Harbor, Maine, USA). All mice were between 28 and 35 days of age at the start of the study. For convenience and consistency in reporting, their age was defined ...
ORGANISM(S): Mus musculus 
2009-09-18 | E-GEOD-17990 | biostudies-arrayexpress
UnknownSelective recruitment designs for improving observational studies using electronic health records.
Not available
S-EPMC8432147 | biostudies-literature
TranscriptomicsTranscription profiling of human intestinal epithelial cell line Caco-2 treated with Lactobacillus plantarum MB452
Effect of Lactobacillus plantarum MB452 on the gene expression of the intestinal epithelial cell line Caco-2 using a reference design Experiment Overall Design: Effect of Lactobacillus plantarum MB452 on the gene expression of the intestinal epithelial cell line Caco-2 using a reference design
ORGANISM(S): Homo sapiens 
2009-10-09 | E-GEOD-18372 | biostudies-arrayexpress
UnknownAbsolute Benefit of Adjuvant Endocrine Therapies for Premenopausal Women With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer: TEXT and SOFT Trials.
Not available
S-EPMC4962708 | biostudies-literature
UnknownScientific novelty beyond the experiment.
Not available
S-EPMC10221578 | biostudies-literature
UnknownAbnormal morphology biases hematocrit distribution in tumor vasculature and contributes to heterogeneity in tissue oxygenation.
Not available
S-EPMC7668105 | biostudies-literature
GenomicsCanadian Prostate Cancer Genome Network
Over 5 years, CPC-GENE will sequence the genomes of 350 intermediate risk prostate cancers to identify genetic signatures that differ in cancers that responded well to treatment compared with those that did not. CPC-GENE will also sequence multiple regions of prostate cancer from the same gland to ...
EGAS00001000900 | EGA
UnknownNOX1 loss-of-function genetic variants in patients with inflammatory bowel disease.
Not available
S-EPMC5924597 | biostudies-literature
GenomicsGlobal epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci
Identifying cis-regulatory elements is important to understand how human pancreatic islets modulate gene expression in physiologic or pathophysiologic (e.g., diabetic) conditions. We conducted genome-wide analysis of DNase I hypersensitive sites, histone H3 lysine methylation marks (K4me1, K4me3, K7...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-23784 | biostudies-arrayexpress
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