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TranscriptomicsGene expression profiles of peripheral blood mononuclear cells from HIV and HCV coinfected patients before and after 24 weeks of combined antiretroviral therapy.
We aim to characterize HIV and HCV coinfected patient response to combined antiretroviral therapy through genome-wide expression profiling of patients' periperhal blood mononuclear cells before and after treatment initiation (baseline and 24 weeks). Individuals with frank cirrhosis were excluded fr...
ORGANISM(S): Homo sapiens 
2014-10-07 | E-GEOD-56619 | biostudies-arrayexpress
UnknownPhase III randomized trial of induction chemotherapy in patients with N2 or N3 locally advanced head and neck cancer.
Not available
S-EPMC4876357 | biostudies-literature
UnknownSouthwest Oncology Group S0008: a phase III trial of high-dose interferon Alfa-2b versus cisplatin, vinblastine, and dacarbazine, plus interleukin-2 and interferon in patients with high-risk melanoma--an intergroup study of cancer and leukemia Group B, Children's Oncology Group, Eastern Cooperative Oncology Group, and Southwest Oncology Group.
Not available
S-EPMC4226807 | biostudies-literature
UnknownIn vitro and in vivo correlation of skin and cellular responses to nucleic acid delivery.
Not available
S-EPMC10010056 | biostudies-literature
TranscriptomicsGene expression signatures of 64 T-ALL patient diagnosis samples
Genetic studies have shown that human T-ALLs can be divided into subgroups that are characterized by unique gene expression signatures and relate to stages of T-cell differentiation at which the leukemic cells arrest. Each molecular subgroup has characteristic genetic abnormalities that cause aberra...
ORGANISM(S): Homo sapiens 
2014-10-14 | E-GEOD-62156 | biostudies-arrayexpress
UnknownComparing sequencing assays and human-machine analyses in actionable genomics for glioblastoma.
Not available
S-EPMC5506390 | biostudies-literature
TranscriptomicsSystems analysis identifies an essential role for SHARPIN in macrophage TLR2 responses (Affymetrix)
Our systems analysis reported here demonstrates that TLR-responses in macrophages are markedly impaired by SHARPIN deficiency, and that SHARPIN controls expression of a subset of TLR2-induced, NF-kB and AP-1 dependent genes that overlaps with those affected by the hypomorphic panr2 mutation in NEMO....
ORGANISM(S): Mus musculus 
2011-08-30 | E-GEOD-29891 | biostudies-arrayexpress
TranscriptomicsSystems analysis identifies an essential role for SHARPIN in macrophage TLR2 responses (Agilent)
Our systems analysis reported here demonstrates that TLR-responses in macrophages are markedly impaired by SHARPIN deficiency, and that SHARPIN controls expression of a subset of TLR2-induced, NF-kB and AP-1 dependent genes that overlaps with those affected by the hypomorphic panr2 mutation in NEMO....
ORGANISM(S): Mus musculus 
2011-08-30 | E-GEOD-29888 | biostudies-arrayexpress
TranscriptomicsDevelopment of gene expression signatures with lncRNAs for 15 T-ALL patients
Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-61863 | biostudies-arrayexpress
UnknownMembrane protein megahertz crystallography at the European XFEL.
Not available
S-EPMC6828683 | biostudies-literature
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