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TranscriptomicsGene expression profiles of HEK293 cells following induction of wild-type and mutated FOXP3
The forkhead DNA-binding protein FOXP3 is critical for the development and suppressive function of CD4+CD25+ regulatory T cells (TREG), which play a key role in maintaining self tolerance. Functionally, FOXP3 is capable of repressing transcription of cytokine genes regulated by the Nuclear Factor of...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-13798 | biostudies-arrayexpress
TranscriptomicsYeast expression data from conditions that inhibit sirtuins
Sir2 is an NAD+-dependent histone deacetylase, and is the founding member of a large, phylogentically conserved, family of such deacetylases called the Sirtuins. The budding yeast, Saccharomyces cerevisiae, harbors 4 paralogs of Sir2, known as Hst1, Hst2, Hst3, and Hst4. Reducing the intracellular N...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-10 | E-GEOD-18488 | biostudies-arrayexpress
UnknownEffect of decentralising childhood tuberculosis diagnosis to primary health centre versus district hospital levels on disease detection in children from six high tuberculosis incidence countries: an operational research, pre-post intervention study.
Not available
S-EPMC11056389 | biostudies-literature
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
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