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ModelsSachse2008_FibroblastInteractingMyocytes
This a model from the article: Electrophysiological modeling of fibroblasts and their interaction with myocytes. Sachse FB, Moreno AP, Abildskov JA. Ann Biomed Eng. year volume page 17999190 , Abstract: E...
2005-01-01 | MODEL7914759868 | BioModels
ModelsBruggeman2005_AmmoniumAssimilation
This a model from the article: The multifarious short-term regulation of ammonium assimilation of Escherichia coli: dissection using an in silico replica. Bruggeman FJ, Boogerd FC, Westerhoff HV. FEBS J. 2005 Apr;272(8):1965-85. 15819889 ...
2024-09-02 | BIOMD0000000217 | BioModels
ProteomicsPTEN DEFICIENCY LEADS TO PROTEASOME ADDICTION, A NOVEL VULNERABILITY IN GLIOBLASTOMA
Glioblastoma (GBM) is the most common primary brain tumor in adults with a median survival of approximately 15 months, therefore, more effective treatment options for GBM are required. To identify new drugs targeting glioblastomas, we performed a high throughput drug screen using patient-derived neu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-12-04 | MSV000086560 | MassIVE
OtherThe Proteome of the Isolated Chlamydia trachomatis Containing Vacuole Reveals a Complex Trafficking Platform Enriched for Retromer Components.
Data from ProteomeXchange, PXD ID: PXD002113. File: 130514_LA_C_92_SAX8.mzml. Published as part of PLoS Pathog. 2015 Jun 4;11(6):e1004883 . From the Abstract: {{i}} Chlamydia trachomatis is an important human pathogen that replicates inside the infected host cell in a unique vacuole, the inclusion....
ORGANISM(S): Homo_sapiens_viruses, Human_female, Chlamydia_trachomatis_l2b_uch_1_proctitis, Chlamydia_trachomatis_l2c 
GPM32310020401 | GPMDB
Resource Reanalysis 
ModelsQueralt2006_MitoticExit_Cdc55DownregulationBySeparase
This model is from the article: Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast. Queralt E, Lehane C, Novak B, Uhlmann F. Cell. 2006 May 19;125(4):719-32. 16713564 , ...
2024-09-02 | BIOMD0000000409 | BioModels
GenomicsChIP-Seq of BCL11A and SOX2 in lung squamous cell carcinoma (LUSC) LK-2 cell line with or without BCL11A knockdown
BCL11A is upregulated in lung squamous cell carcinoma (LUSC) but not in lung adenocarcinoma (LUAD). BCL11A interacts with SOX2 at protein level. ChIP-Seq experiment was performed for BCL11A and SOX2 in LUSC LK-2 control or BCL11A-KD cell line in order to identify their role in LUSC pathology.
ORGANISM(S): Homo sapiens 
2018-07-05 | E-MTAB-6958 | biostudies-arrayexpress
TranscriptomicsExpression analysis of human ex vivo cultivated urothelial carcinoma samples transduced with a trivalent adenoviral vector (Im02) for activation of the immune tumor microenvironment.
The trivalent adenoviral vector Im02 encodes the cDNAs for human 4-1BBL, IL-12 and IL-2. This vector was designed to change the immune tumor microenvironment. In this study we investigated the immune stimulating effect of Im02 on human primary urothelial cancer specimens or normal urothelium by RNAS...
ORGANISM(S): Homo sapiens 
2020-06-18 | E-MTAB-7659 | biostudies-arrayexpress
TranscriptomicsExpression analysis of human ex vivo cultivated urothelial carcinoma samples transduced with a trivalent adenoviral vector (Im02) for activation of the immune tumor microenvironment.
The trivalent adenoviral vector Im02 encodes the cDNAs for human 4-1BBL, IL-12 and IL-2. This vector was designed to change the immune tumor microenvironment. In this study we investigated the immune stimulating effect of Im02 on human primary urothelial cancer specimens or normal urothelium by micr...
ORGANISM(S): Homo sapiens 
2021-01-01 | E-MTAB-7623 | biostudies-arrayexpress
TranscriptomicsExpression-analysis of human peripheral blood mononuclear cells (PBMC) cocultivated with RT-4 cells transduced with a trivalent adenoviral vector (Im02) for expression of 4-1BBL, IL-12 and IL-2
The trivalent adenoviral vector Im02 encodes the cDNAs for human 4-1BBL, IL-12 and IL-2. This vector was designed to change the immune tumor microenvironment. At the outset, we investigated the immune stimulating effect of Im02 transduced urothelial cancer cells (RT-4). Human PBMCs of a healthy dono...
ORGANISM(S): Homo sapiens 
2021-01-01 | E-MTAB-7615 | biostudies-arrayexpress
GenomicsRelapsed and Primary Neuroblastoma DAC
Data Access Committee EGAC00001000373
EGAC00001000373 | EGA
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