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TranscriptomicsOvalbumin sensitized and challenged induces differential gene expression in mouse lungs
To gain insight into the promoting effect of ultrafine particle inhalation on development and progression of allergic asthma, we selected an experimental approach involving exposure to ultrafine carbon particles (UCP) and gene expression profiling of lungs from mice with experimental, ovalbumin indu...
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-6496 | biostudies-arrayexpress
TranscriptomicsUCP exposure of ovalbumin sensitized and challenged mice
To gain insight into the promoting effect of ultrafine particle inhalation on development and progression of allergic asthma, we selected an experimental approach involving exposure to ultrafine carbon particles (UCP) and gene expression profiling of lungs from mice with experimental, ovalbumin indu...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-6571 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression profiles between human and mouse monocyte subsets [mouse data]
Human and mouse blood each contain two monocyte subsets. Here, we investigated the extent of their similarity using a microarray approach. Approximately 300 genes in human and 550 genes in mouse were differentially expressed between subsets. More than 130 of these gene expression differences were co...
ORGANISM(S): Mus musculus 
2009-12-03 | E-GEOD-17256 | biostudies-arrayexpress
TranscriptomicsGene expression profiling on bronchoalveolar lavage (BAL) cells treated with all-trans-retinoic acid (ATRA)
All-trans retinoic acid (ATRA) is a potent retinoid, which has been used successfully in different clinical settings as a potential drug to treat COPD and emphysema. In alveolar macrophages, ATRA selectively down-regulates MMP-9 and up-regulates TIMP-1 expression. In the present study, we analyzed a...
ORGANISM(S): Homo sapiens 
2010-09-04 | E-GEOD-23704 | biostudies-arrayexpress
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