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UnknownA randomized, phase II, biomarker-selected study comparing erlotinib to erlotinib intercalated with chemotherapy in first-line therapy for advanced non-small-cell lung cancer.
Not available
S-EPMC3179254 | biostudies-literature
ProteomicsLabel-free proteome analysis of small extracellular vesicles (sEV) expressing different HRS mutants.
Label-free proteome analysis of small extracellular vesicles (sEV) derived from WM9 cells expressing different HRS mutants: wild type (HRSWT), phospho-deficient (HRSS345A), and phospho-mimetic mutant HRS (HRSS345D).
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-02-16 | MSV000088846 | MassIVE
UnknownElectron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly.
Not available
S-EPMC5973842 | biostudies-literature
ProteomicsHepatocyte mitochondrial NAD+ content is limiting for liver regeneration
Supplemental NAD+ precursors show metabolic and functional benefits in rodent models of disease and are being explored as potential therapeutics in human studies. However, the wide range of processes that involve NAD+ in every cell and subcellular compartment make it difficult to narrow down mechani...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-08-15 | MSV000098839 | MassIVE
TranscriptomicsEffects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Calorie restriction (CR) is the most robust non-genetic intervention to universally delay the onset of age-related diseases and extend mean and maximum lifespan. However, species, strain, sex, diet, age of onset, and level of CR are emerging as important variables to consider for a successful CR res...
ORGANISM(S): Mus musculus 
2016-06-27 | E-GEOD-81959 | biostudies-arrayexpress
TranscriptomicsHigh-resolution copy number analysis of medulloblastoma
We used high-resolution SNP genotyping to identify regions of genomic gain and loss in the genome of 212 medulloblastomas, a malignant pediatric brain tumor. Focal amplifications of fifteen known oncogenes and focal deletions of twenty known tumor suppressor genes (TSG) were revealed, most not prev...
ORGANISM(S): Homo sapiens 
2010-04-06 | E-GEOD-14437 | biostudies-arrayexpress
TranscriptomicsResveratrol Diet Aging (Heart, Liver, Muscle and Fat Tissue)
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending lifespan A small molecule that safely mimics the ability of dietary restriction (DR) to delay age-related diseases in laboratory animals is greatly sought after. We and others ha...
ORGANISM(S): Mus musculus 
2008-08-04 | E-GEOD-11845 | biostudies-arrayexpress
UnknownA high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response.
Not available
S-EPMC8959399 | biostudies-literature
UnknownProteogenomic Characterization of Endometrial Carcinoma.
Not available
S-EPMC7233456 | biostudies-literature
UnknownProteogenomic insights suggest druggable pathways in endometrial carcinoma.
Not available
S-EPMC10631452 | biostudies-literature
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