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TranscriptomicsRNAseq transcriptome data from reprogramming human CD34+ cells to iPS
We reprogrammed human CD34+ cells from cord blood using a lentiviral vector encoding OCT4, SOX2 and KLF4.We collected RNA from parental CD34+ cells (3samples), reprogramming timepoints (9 timepoints), iPS clones derived from this experiment (6 clones), and human ES cell lines (9 samples). All sample...
ORGANISM(S): Homo sapiens 
2014-05-24 | E-GEOD-57866 | biostudies-arrayexpress
TranscriptomicsRNA-seq of naive and primed ES cells (NHSM)
Here we propose a set of molecular criteria for evaluating the naive human pluripotent state. We show by RNA-seq that transcription of transposable elements provides a sensitive measure of the concordance between pluripotent stem cells and early human development. RNA-seq of 3 naive ES samples in NH...
ORGANISM(S): Homo sapiens 
2016-08-16 | E-GEOD-85689 | biostudies-arrayexpress
TranscriptomicsRNA-seq of naive and primed ES cells
Here we propose a set of molecular criteria for evaluating the naive human pluripotent state. We show by RNA-seq that transcription of transposable elements provides a sensitive measure of the concordance between pluripotent stem cells and early human development. RNA-seq of 4 naive ES samples in 4i...
ORGANISM(S): Homo sapiens 
2016-07-15 | E-GEOD-83765 | biostudies-arrayexpress
GenomicsNaive Pluripotent Stem Cells Display Transcriptional and Epigenetic Signatures of the Human Pre-Implantation Embryo
Significant interest has been devoted to the isolation of human pluripotent stem cells displaying the naive state of mouse embryonic stem cells. However, to what extent naive human cells isolated in culture resemble pluripotent cells in vivo remains unclear. Here we present three lines of evidence i...
ORGANISM(S): Homo sapiens 
2016-07-18 | E-GEOD-75868 | biostudies-arrayexpress
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