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TranscriptomicsHighly Pathogenic Avian Influenza Viruses Avoid Effective Inflammatory Response of Human Macrophages
Macrophages were infected with low (PR8) and high pathogenic influenza viruses (FPV and H5N1). To our surprise a genome-wide comparative systems biology approach revealed that in contrast PR8 infections with HPAIV H5N1 and FPV result in a reduced immune response of human macrophages contradicting a ...
ORGANISM(S): Homo sapiens 
2012-05-28 | E-GEOD-27702 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of HUVEC infected with Influenza virus
To delineate specific patterns of signaling networks activated by H5N1 we used a comparative systems biology approach analyzing gene expression in endothelial cells infected with three different human and avian influenza strains of high and low pathogenicity. HUVECs were infected with either PR8, F...
ORGANISM(S): Homo sapiens 
2009-12-30 | E-GEOD-13637 | biostudies-arrayexpress
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