Fu Jinlei J - OmicsDI

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Publication Date

2025 (2)

Lab affiliation

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province 730046, PR China (2)

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The PP2A-2 holoenzyme orchestrates daughter cell emergence during cytokinesis in Toxoplasma gondii

Toxoplasma gondii is a significant pathogen affecting both humans and animals, with clinical symptoms primarily driven by the uncontrolled proliferation of tachyzoites. In this study, we reveal the essential role and functional plasticity of the PP2A-2 holoenzyme in orchestrating daughter cell emerg...

ORGANISM(S): Toxoplasma gondii

2025-08-21 | PXD064226 | Pride

Toxoplasma gondii pp2a-2 phosphatase cytokinesis cell division daughter cell emergence phosphoproteomics

AP2X-1 is a negative regulator of Toxoplasma gondii sexual commitment

Toxoplasma gondii is a widespread protozoan with a complex life cycle, characterized by transitions between various hosts and developmental stages, each tailored to a specific niche within its host. However, the regulatory mechanisms governing these life cycle transitions are not well understood. In...

ORGANISM(S): Toxoplasma gondii ME49

2025-06-29 | PXD065585 | Pride

Toxoplasma gondii ap2x-1 hdac3/morc complex gene expression sexual development transcription

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