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TranscriptomicsExpression data from pancreatic CD45+ immune cells
The aim of this study was to explore what molecular and cellular processes predicate the conversion from insulitis to diabetes. The transcriptional profiles of CD45+ immune cells collected from pancreas of a cohort of age-matched female mice, which were scanned by MRI to determine the risk of diabet...
ORGANISM(S): Mus musculus 
2012-01-14 | E-GEOD-35096 | biostudies-arrayexpress
TranscriptomicsGene profiling data of CD4+ T cells doubly transduced with EOS+LEF1 or GATA1+SATB1
The transcription factor FoxP3 partakes dominantly in the specification and function of FoxP3+ CD4+ T regulatory cells (Tregs), but is neither strictly necessary nor sufficient to determine the characteristic Treg transcriptional signature. Computational network inference and experimental testing as...
ORGANISM(S): Mus musculus 
2012-08-23 | E-GEOD-40277 | biostudies-arrayexpress
TranscriptomicsGene profiling data of CD4+ T cells transduced with FOXP3 and candidate cofactors
The transcription factor FoxP3 partakes dominantly in the specification and function of FoxP3+ CD4+ T regulatory cells (Tregs), but is neither strictly necessary nor sufficient to determine the characteristic Treg transcriptional signature. Computational network inference and experimental testing as...
ORGANISM(S): Mus musculus 
2012-08-23 | E-GEOD-40274 | biostudies-arrayexpress
TranscriptomicsGene profiling data of CD4+ T cells transduced with FOXP3 and GATA1, then sorted into different fractions, based on the expression of Thy1.1 (FOXP3)
The transcription factor FoxP3 partakes dominantly in the specification and function of FoxP3+ CD4+ T regulatory cells (Tregs), but is neither strictly necessary nor sufficient to determine the characteristic Treg transcriptional signature. Computational network inference and experimental testing as...
ORGANISM(S): Mus musculus 
2012-08-23 | E-GEOD-40276 | biostudies-arrayexpress
GenomicsGenome-wide maps of FoxP3 binding in transduced CD4+ T cells
The transcription factor FoxP3 partakes dominantly in the specification and function of FoxP3+ CD4+ T regulatory cells (Tregs), but is neither strictly necessary nor sufficient to determine the characteristic Treg transcriptional signature. Computational network inference and experimental testing as...
ORGANISM(S): Mus musculus 
2012-08-23 | E-GEOD-40238 | biostudies-arrayexpress
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