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Cajanin stilbene acid (CSA) was previously shown to induce cytotoxicity against cancer cells. We have employed microarray gene expression profiling to identify deregulated genes in MCF-7 breast cancer cells upon treatment with CSA and its synthetic derivatives (CSA6, CSA9, CSA19). TGM2 gene encoding...
ORGANISM(S): Homo sapiens 
Through digital rectal examinations and routine prostate-specific antigen (PSA) screening, early treatment of prostate cancer has become possible. However, prostate cancer is a complex and heterogeneous disease. In many patients, cancer cells can invade adjacent tissues and metastasize to other tiss...
ORGANISM(S): Homo Sapiens 
2021-09-05 | PXD028211 |
Precise regulation of mitochondrial fusion and fission is essential for cellular activity and animal development. Imbalances between these processes can lead to fragmentation and loss of normal membrane potential in individual mitochondria. In this study, we show that MIRO-1 is stochastically elevat...
ORGANISM(S): Caenorhabditis Elegans 
2023-05-10 | PXD040748 |
Although people of all ages are susceptible to COVID-19, children usually develop less severe disease than adults. Little is known about the pathogenesis of COVID-19 in children. Herein, we conduct the plasma proteomic and metabolomic profiling of a cohort of COVID-19 children patients with mild sym...
ORGANISM(S): Homo Sapiens 
2021-06-28 | PXD026962 |
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