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ProteomicsProteomics of Fuchs Endothelial Corneal Dystrophy support that the extracellular matrix of Descemet¹s membrane is Disordered
Fuchs’ endothelial corneal dystrophy is major corneal disorder in the western world affecting the innermost part of the cornea, which leads to visual impairment. The morphological changes observed in Fuchs’ endothelial corneal dystrophy is well described, however, much less in known of the pathology...
ORGANISM(S): Homo sapiens (Human) 
2014-05-27 | PXD000746 | Pride
Itraq quantification Fuchs' endothelial corneal dystrophy Xic quantification 
GenomicsA Genome-Wide Association Study of Fuchs' Endothelial Corneal Dystrophy (FECD)

Fuchs' Endothelial Corneal Dystrophy (FECD) is a common disease that results in loss of vision associated with progressive corneal edema and loss of corneal transparency. In the initial stages of the disease, excrescences on Descemet's membrane with the appearance of an abnormal posterior...

phs000421.v1.p1 | EGA
ProteomicsProtein co-immmunoprecipitation using antibodies specific for the antimicrobial peptide FsPDF2 from Fagus sylvatica
To assess the specificity of the antibodies used in the quantitative sandwich ELISA, co-immunoprecipitation (CoIP) was performed. Proteins binding to these antibodies were detected using LC-MS/MS in DDA mode.
ORGANISM(S): Fagus sylvatica 
2026-06-08 | PXD060631 | Pride
Co- immunoprecipitation (coip) Antimicrobial peptides Fagus sylvatica 
UnknownPreoperative edema severity affects outcomes after Descemet membrane endothelial keratoplasty for Fuchs endothelial corneal dystrophy: a cohort study.
Not available
S-EPMC11871603 | biostudies-literature
ProteomicsBlockade of mitochondrial components release by exosome pathway promotes the pathogenesis of Fuchs endothelial corneal dystrophy
Fuchs endothelial corneal dystrophy (FECD) is the leading indication of corneal transplantation worldwide and the focus of pathogenesis has been on the corneal endothelium. Instead of cellular analysis, we aimed to identify the protein changes of aqueous humor (AH) in patients with FECD and investig...
ORGANISM(S): Homo sapiens (Human) 
2026-01-23 | PXD065309 | Pride
Fuchs endothelial corneal dystrophy  proteomics  aqueous humor  corneal endothelium  mitochondrial quality control 
TranscriptomicsExpression Profiling of Dll1 mutant mouse lines on different genetic background
The evolutionarily conserved Delta-Notch cell-cell signal-transduction pathway regulates the determination of various cell fates, which are important for the morphogenesis and development of numerous organs and tissues in many vertebrates and invertebrates. The Dll1 gene was mutated by homologous r...
ORGANISM(S): Mus musculus 
2009-01-01 | E-GEOD-11867 | biostudies-arrayexpress
ProteomicsStructural and Functional Analysis of ASFV pI73R Reveals GNB1 Binding and Host Gene Modulation
African swine fever virus (ASFV) causes a highly fatal disease in domestic pigs, resulting in substantial economic losses to the global swine industry. Vaccine development continues to be hindered by limited characterization of viral proteins and their functional redundancies. In this study, we empl...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-01-05 | PXD066360 | Pride
Gnb1 Asfv Virus-host interaction African swine fever virus Protein-protein interaction Pi73r Gene expression 
UnknownA pseudorabies virus recombinant simultaneously lacking the major tegument proteins encoded by the UL46, UL47, UL48, and UL49 genes is viable in cultured cells.
Not available
S-EPMC262591 | biostudies-literature
UnknownFMX - the Frontier Microfocusing Macromolecular Crystallography Beamline at the National Synchrotron Light Source II.
Not available
S-EPMC7941291 | biostudies-literature
UnknownCTG18.1 Expansion in TCF4 Increases Likelihood of Transplantation in Fuchs Corneal Dystrophy.
Not available
S-EPMC5138126 | biostudies-literature
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