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UnknownPhase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma.
Not available
S-EPMC6075856 | biostudies-literature
Proteomics53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
53BP1 governs a specialized, context-specific branch of the classical non-homologous end joining DNA double-strand break repair pathway. Mice lacking 53bp1 (also known as Trp53bp1) are immunodeficient owing to a complete loss of immunoglobulin class-switch recombination, and reduced fidelity of long...
ORGANISM(S): Mus musculus (Mouse) 
2018-07-26 | PXD009650 | Pride
Rev7 shieldin 
TranscriptomicsTranscription profiling of human liver transplant patients reveals a signature that could discriminate tolerant recipients from immunosuppression-dependent patients
mmunosuppressive drugs can be completely withdrawn in up to 20% of liver transplant recipients, commonly referred to as ‘operationally’ tolerant. Immune characterization of these patients, however, has not been performed in detail, and we lack tests capable of identifying tolerant patients among...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-11881 | biostudies-arrayexpress
Unknown53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.
Not available
S-EPMC6989217 | biostudies-literature
TranscriptomicsMOLECULAR CHARACTERIZATION OF LIVER ALLOGRAFTS FROM OPERATIONALLY TOLERANT TRANSPLANT RECIPIENTS (Affymetrix)
In clinical organ transplantation complete cessation of immunosuppressive therapy can be successfully accomplished in selected recipients providing a proof-of-principle that allograft tolerance is attainable in humans. The intra-graft molecular pathways associated with human allograft tolerance, how...
ORGANISM(S): Homo sapiens 
2012-01-09 | E-GEOD-26622 | biostudies-arrayexpress
TranscriptomicsMOLECULAR CHARACTERIZATION OF LIVER ALLOGRAFTS FROM OPERATIONALLY TOLERANT TRANSPLANT RECIPIENTS (Illumina)
In clinical organ transplantation complete cessation of immunosuppressive therapy can be successfully accomplished in selected recipients providing a proof-of-principle that allograft tolerance is attainable in humans. The intra-graft molecular pathways associated with human allograft tolerance, how...
ORGANISM(S): Homo sapiens 
2012-01-09 | E-GEOD-26625 | biostudies-arrayexpress
TranscriptomicsMolecular Characterization of Acute Cellular Rejection Occurring during Intentional Immunosuppression Withdrawal in Liver Transplantation
Acute cellular rejection occurs frequently during the first few weeks following liver transplantation. During this period its molecular phenotype is confounded by pro-inflammatory events elicited by surgery, ischemia-reperfusion injury and early post-transplant complications. To unambiguously define...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-70305 | biostudies-arrayexpress
UnknownAntitumor immune response during glioma virotherapy.
Not available
S-EPMC7594555 | biostudies-literature
UnknownCytotoxin and pyrogenic toxin superantigen gene profiles of Staphylococcus aureus associated with subclinical mastitis in dairy cows and relationships with macrorestriction genomic profiles.
Not available
S-EPMC1081256 | biostudies-literature
UnknownA human-specific regulatory mechanism revealed in a pre-implantation model.
Not available
S-EPMC12589118 | biostudies-literature
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