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TranscriptomicsIdentification of genes up-regulated by the overexpression of HSF1 in human HeLa cells
To analyze target genes of human heat shock transcription factor 1 (HSF1), we first generated two independent HeLa clones (RDT1 and RDT2) expressing an actively mutated hHSF1 (hHSF1?RDT), which lacks the regulatory domain that masks its activation domain and possesses a glutamic acid at amino acid 3...
ORGANISM(S): Homo sapiens 
2010-09-22 | E-GEOD-19797 | biostudies-arrayexpress
TranscriptomicsIdentification of genes regulated by knockdown of HSF1 or RPA1
Transcription factor access to regulatory elements is prevented by the nucleosome. Heat shock factor 1 (HSF1) is a winged helix transcription factor that plays roles in control and stressed conditions by gaining access to target elements, but mechanisms of HSF1 access have not been well known in mam...
ORGANISM(S): Mus musculus 
2012-12-31 | E-GEOD-38412 | biostudies-arrayexpress
ProteomicsTRRAP-interacting proteins during heat shock
Project description: HeLa cells and cells stably expressing hTRRAP-3xFlAG were subjected to mass spectrometry (MS) analysis. Briefly, Cells were treated or untreated with heat shock at 42°C for 30 min, and TRRAP was immunoprecipitated from these cell extracts with 60 ul anti-FLAG M2 affinity gels by...
ORGANISM(S): Homo Sapiens (human) 
2022-06-19 | PXD031822 | JPOST Repository
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