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TranscriptomicsInhibitor of apoptosis proteins as promising therapeutic targets in chronic lymphocytic leukemia
Inhibitor of apoptosis (IAP) proteins are expressed at high levels in CLL cells and may contribute to evasion of cell death leading to poor therapeutic outcome. Of note, prognostic unfavourable cases with e.g. non-mutated VH-status and TP53 mutation responded significantly better to BV6 than samples...
ORGANISM(S): Homo sapiens 
2015-03-31 | E-GEOD-62533 | biostudies-arrayexpress
TranscriptomicsTranscriptomic signatures of risk genes implicated in psychiatric disorders during neuronal differentiation
Susceptibility genes for Autism Spectrum Disorder (ASD), Fragile X Syndrome (FXS), monogenetic disorders with intellectual disabilities (ID) or schizophrenia (SCZ) converge on processes related to neuronal function and differentiation. Furthermore, ASD risk genes are enriched for FMRP (Fragile X Men...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-69838 | biostudies-arrayexpress
TranscriptomicsAffymetrix CytoscanHD Arrays of 113 Osteosarcoma Samples
Osteosarcoma (OS) is the most common primary malignant tumor of bone; it occurs most commonly in the metaphyseal regions of long bones in adolescents and young adults. Conventional osteosarcoma is characterized by complex karyotypes with a high degree of aneuploidy and numerous structural aberration...
ORGANISM(S): Homo sapiens 
2015-11-09 | E-MTAB-3998 | biostudies-arrayexpress
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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