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TranscriptomicsDiscovery of novel recurrent mutations and rearrangements in early T-cell precursor acute lymphoblastic leukemia by whole genome sequencing
Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole genome sequencing of tumour and normal DNA from 12 children with ETP ALL and assessed the frequency of somatic alterations in 52 ETP and 42 non-ETP T-ALL samples by...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-28703 | biostudies-arrayexpress
GenomicsEstrogen Receptor Positive Breast Cancer: Aromatase Inhibitor Response Study

Highly variable outcomes are observed in patients with estrogen receptor positive (ER+) breast cancer who undergo preoperative estrogen deprivation therapy with aromatase inhibitors (AI). In this study, 46 tumor and normal genomes and 31 exomes of participants selected from two clinical trials of...

phs000472.v1.p1 | EGA
TranscriptomicsParadigm Test Set
This SuperSeries is composed of the following subset Series: GSE35186: Paradigm Test Set Expression Array GSE35189: Paradigm Test Set aCGH Array Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-06-20 | E-GEOD-35191 | biostudies-arrayexpress
TranscriptomicsBRC77 Agilent Gene Expression Arrays
Agilent 44K whole genome studies were used to correlate gene expression values with mutations found in massively parallel sequencing experiments. 77 patients were profiled using Agilent's two-color microarray platform. Tumor(cy5) was co-hybridized to a reference(cy3).
ORGANISM(S): Homo sapiens 
2012-06-20 | E-GEOD-29442 | biostudies-arrayexpress
UnknownWhole-genome analysis informs breast cancer response to aromatase inhibition.
Not available
S-EPMC3383766 | biostudies-literature
UnknownBRC77 Agilent Gene Expression Arrays
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-29442 | biostudies-other
UnknownlncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.
Not available
S-EPMC6143179 | biostudies-literature
UnknownReconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig.
Not available
S-EPMC7002414 | biostudies-literature
UnknownThe transcription factor encyclopedia.
Not available
S-EPMC3439975 | biostudies-literature
UnknownA high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response.
Not available
S-EPMC8959399 | biostudies-literature
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