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TranscriptomicsExpression data from human unbilical endothelial cells (HUVEC) irradiated with X-ray
To understand the molecular mechanism underlying inflammatory reaction in vascular system post exposure to ionizing radiation, we carried out microarray analysis in HUVEC exposed with X-ray HUVEC were irradiated with X-ray (2.5 Gy) and then cultured for 6, 12, and 24 hr. Total RNA were extracted fro...
ORGANISM(S): Homo sapiens 
2016-01-21 | E-GEOD-76484 | biostudies-arrayexpress
TranscriptomicsExpression data from follicle associated epithelium (FAE) of small intestine in wild type C57BL/6 mice or mice depleted with RBP-J (by VillinCre-Rbpjflox/flox)
To investigate the role of RBP-J in regulating epithelial cell differention in small intestine, we isolated FAE from mice depleted with RBP-J FAE were isolated from mice described above. Total RNA were extracted from the tissue by QIAGEN Rneasy mini kit.
ORGANISM(S): Mus musculus 
2014-09-04 | E-GEOD-61058 | biostudies-arrayexpress
GenomicsGenome-wide measurement of acetylated histone H3 in naïve cells under Treg-inducing conditon
To investigate the molecular mechanism how butyrate promoter differentiation of naïve T cells into regulatory T cells Examination of acetylated histone H3 during the differentiation of regulatory T cells in the presence or absence of butyrate
ORGANISM(S): Mus musculus 
2013-11-20 | E-GEOD-49653 | biostudies-arrayexpress
TranscriptomicsExpression data from CD4+ NaM-CM-/ve T cells under Treg-inducing condition in the presence or absence of butyrate
Commensal bacteria shapes gut immune system. Colonization bacteria increase the frequency of regulatory T cells, however, the molecular mechanisms has not yet been unknown. To reveal the mechanism, we isolated NaM-CM-/ve CD4+ T cells from spleen of C57BL/6 mice and cultured the cells under Treg-indu...
ORGANISM(S): Mus musculus 
2013-11-20 | E-GEOD-49619 | biostudies-arrayexpress
TranscriptomicsIdentification of genes responsive to mild hyperthermia in human skin normal fibroblast Hs68 cells
Hyperthermia is widely used to treat patients with various cancers. Here, the effects of heat stress at 41M-BM-0C for 30 min (mild hyperthermia) on the gene expression in Hs68 human skin normal fibroblast cells were investigated using an Affymetrix GeneChip system. The cells were treated with mild h...
ORGANISM(S): Homo sapiens 
2012-07-12 | E-GEOD-39177 | biostudies-arrayexpress
TranscriptomicsIdentification of genes responsive to mild hyperthermia in human normal fibroblast OUMS-36 cells
Hyperthermia is widely used to treat patients with various cancers. Here, the effects of heat stress at 41M-BM-0C for 30 min (mild hyperthermia) on the gene expression in OUMS-36 human normal fibroblast cells were investigated using an Affymetrix GeneChip system. The cells were treated with mild hyp...
ORGANISM(S): Homo sapiens 
2012-07-12 | E-GEOD-39178 | biostudies-arrayexpress
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