Gains of function

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Unknown (1120)
Transcriptomics (151)
Genomics (149)
Proteomics (27)
Metabolomics (11)
Methylation profiling (8)
Other (2)
Models (1)
Clinical (1)

Organisms

Homo sapiens (75)
Mus musculus (72)
Drosophila melanogaster (10)
Rattus norvegicus (7)
Entamoeba histolytica (5)
Arabidopsis thaliana (4)
Schizosaccharomyces pombe (4)
Solanum tuberosum (3)
Heterocephalus glaber (3)
Sus scrofa (3)
Bathyergus suillus (2)
Yersinia pestis (2)
Bos taurus (2)
Neurospora crassa (2)
Butyrivibrio proteoclasticus B316 (1)
Xerophyta humilis (1)
Sus scrofa domesticus (1)
Pimephales promelas (1)
Francisella tularensis subsp. holarctica LVS (1)
Helicoverpa armigera (1)
Hordeum vulgare (1)
Hansenula anomala (1)
Pseudomonas aeruginosa (1)
Pan troglodytes (1)
Callithrix jacchus (1)
Macaca mulatta (1)
Danio rerio (1)
Caenorhabditis elegans (1)
Mus (1)
Gallus gallus (1)

Organisms

Mus musculus (35)
Homo sapiens (35)
Schizosaccharomyces pombe (4)
Arabidopsis thaliana (4)
Neurospora crassa (2)
Caenorhabditis elegans (2)
Hansenula anomala (1)
fermentation metagenome (1)
Pseudomonas aeruginosa (1)
Sus scrofa (1)
Danio rerio (1)
Rattus norvegicus (1)

Repository

biostudies-arrayexpress (115)
ENA (108)
geo (84)
pride (23)
MetaboLights (11)
EGA (5)
MassIVE (3)
BioModels (1)
iProX (1)

Tissue

Cell culture (13)
Bone marrow (2)
Epithelial cell (2)
Blood (1)
Blood plasma (1)
Blood platelet (1)
Brain (1)
Bronchial epithelial cell (1)
Bronchoalveolar lavage (1)
Cecum (1)
Cell suspension culture (1)
Colon (1)
Common myeloid progenitor (1)
Heart (1)
Kidney (1)
Liver (1)
Lung (1)
Macrophage (1)
Malignant cell (1)
Plant cell (1)
Platelet (1)
Pollen (1)
Rectum (1)
Skeletal muscle cell (1)
Skeletal muscle tissue of trunk (1)
Spleen (1)
Sputum (1)
Stomach (1)

Disease

Retinoblastoma (1)
ER positive breast cancer (1)
Hepatoblastoma (1)
WT (1)
Cachexia (1)
Acute myeloid leukemia (1)
Brain glioblastoma multiforme (1)
Glioblastoma (1)

Technology Type

Mass Spectrometry (23)
Mass spectrometry (9)
Bottom-up proteomics (9)
Shotgun proteomics (9)
Data-independent acquisition (3)
Mass spectrometry assay (2)
Data-dependent acquisition (2)
Gel-based experiment (2)
Affinity proteomics (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
SWATH MS (1)

Instrument Platform

Liquid Chromatography MS - positive - reverse phase (7)
Liquid Chromatography MS - negative - reverse phase (6)
Illumina NovaSeq 6000 (5)
Pacbio Revio (2)
PromethION (2)
GenePix 4000B [Axon Instruments] (2)
Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice/ Thermo Fisher Scientific (1)
Macrogen (1)
Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice (1)
428 [Affymetrix] (1)
Illumina HiSeq 2500 (1)
Q Exactive HF (1)
Q Exactive Plus (1)
TripleTOF 6600 (1)
Liquid Chromatography Tandem MS (LC-MS/MS) (1)
Liquid Chromatography MS - negative - reverse phase - SYNAPT HDMS (Waters) (1)
Liquid Chromatography MS - positive - reverse phase - SYNAPT HDMS (Waters) (1)
Gas Chromatography MS - positive (1)
Liquid Chromatography MS - alternating - hilic (1)
Liquid Chromatography MS - negative - HILIC (1)
Liquid Chromatography MS - positive - HILIC (1)

Publication Date

2025 (33)
2026 (28)
2015 (22)
2013 (20)
2010 (16)
2024 (13)
2019 (12)
2011 (11)
2012 (9)
2022 (8)
2016 (8)
2014 (8)
2020 (7)
2018 (7)
2009 (7)
2008 (7)
2023 (7)
2017 (5)
2007 (4)
2006 (2)
2005 (2)
2021 (2)

UNIPROT ID/AC

Q94BT6 (1)
Q9SQI2 (1)
Q9LKL2 (1)
Q8L500 (1)
Q93WK5 (1)
Q6R0H1 (1)
P92973 (1)

CHEBI ID

CHEBI:17822 (2)
CHEBI:16811 (2)
CHEBI:28300 (2)
CHEBI:17859 (2)
CHEBI:15891 (2)
CHEBI:18237 (2)
CHEBI:16449 (2)
CHEBI:35222 (1)
CHEBI:36080 (1)
CHEBI:33699 (1)
CHEBI:170067 (1)
CHEBI:21601 (1)
CHEBI:28800 (1)
CHEBI:2089 (1)
CHEBI:1230 (1)
CHEBI:2124 (1)
CHEBI:63154 (1)
CHEBI:74767 (1)
CHEBI:16830 (1)
CHEBI:73040 (1)
CHEBI:30830 (1)
CHEBI:143269 (1)
CHEBI:17057 (1)
CHEBI:12937 (1)
CHEBI:89312 (1)
CHEBI:49059 (1)
CHEBI:25801 (1)
CHEBI:33830 (1)
CHEBI:22605 (1)
CHEBI:28260 (1)

Metabolite Name

1-(2-(4-Morpholinyl)ethyl)-3-(1-naphthoyl) indole (2)
Dihydro-5-pentyl-2(3H)-furanone (2)
5-Carboxy-2'-deoxyuridine (2)
Cis-3-Hexenyl pyruvate (2)
Selachyl alcohol (2)
Tildipirosin (2)
Cis-Vaccenic acid (2)
Necatorine (2)
Hexadecenal (2)
Cinncassiol C2 (2)
Allylestrenol (2)
Arg-Thr-Lys-Arg (2)
Nafazatrom (2)
Dehydrocurdione (2)
5alpha-Androstane-3beta,17beta-diol (2)
Alpha-Bisabolol oxide A (2)
Rollidecin D (2)
Armillarilin (2)
Phenylbutyrylglutamine (2)
Scopolamine (2)
Glycyrrhetinic Acid (2)
2,3-Dihydroxycarbamazepine (2)
9-Oxo-nonanoic acid (2)
3-Oxo-2-(2-entenyl)cyclopentaneoctanoic acid (2)
4-Decan-4-Ylbenzenesulfonic Acid (2)
Furanogermenone (2)
Deoxycholylphenylalanine (2)
Glutamylleucine (2)
Glutamylisoleucine (2)
Amastatin (2)

First Public Date

2025 (19)
2026 (17)
2024 (13)
2019 (13)
2021 (9)
2014 (9)
2018 (7)
2017 (6)
2020 (5)
2022 (4)
2013 (3)
2023 (1)
2016 (1)
2015 (1)

Modelling Approach

Ordinary differential equation model (1)

Study status

Not provided (1)

Lab affiliation

Molecular Genetics, RPTU Kaiserslautern, Germany (6)
Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Department of Medicine, Brigham Women's Hospital, Harvard Medical School, Boston, MA, 02115, United States (1)
Chinese Academy of Agricultural Sciences (1)
College of Agriculture/Hubei Key Laboratory of Waterlogging Disaster and Agricultural Use of Wetland, Yangtze University, Jingzhou, Hubei 434025, China (1)
Department of Biochemistry, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany (1)
Department of Biological Sciences, University of Alberta (1)
Dr.Eitan Lerner's lab, The Department of Biological Chemistry The Alexander Silberman Institute for Life Sciences, The Hebrew University of Jerusalem ISRAEL (1)
Experimental Radiation Oncology department, The University of Texas MD Anderson Cancer Center (1)
Finley and Gygi lab Cell Biology Department Harvard Medical School US (1)
German Cancer Research Center (DKFZ), Heidelberg, Germany Heidelberg University, Medical Faculty, Heidelberg, Germany (1)
Group Director OMICS, Integrated Bioanalysis AstraZeneca R&D / Clinical Pharmacology & Safety Sciences 121 Oyster Point Blvd. South San Francisco, CA 94080, USA (1)
Imperial College London (1)
Laboratoire de Spectrométrie de Masse Protéomique (LSMP) Institut Curie (1)
Leibniz-Institut für Analytische Wissenschaften (ISAS), Dortmund, Germany (1)
Liverpool John Moores University (1)
Molecular Genetics, RPTU Kaiserslautern (1)
Université Paris Cité, CNRS, Institut Jacques Monod, F-75013 Paris, France (1)
Yale School of Medicine (1)