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TranscriptomicsLGR5 positivity defines stem-like cells in colorectal cancer [aCGH]
Lgr5-EGFP-IRES-Cre-ERT2 mice were exposed to azoxymethane/dextrane sodium sulfate (AOM/DSS) which induces inflammation-driven colon tumors. Tumors were then flow-sorted into fractions of epithelial cells that expressed high or low levels of Lgr5. To exclude that transcriptional differences between L...
ORGANISM(S): Mus musculus 
2013-05-07 | E-GEOD-46711 | biostudies-arrayexpress
TranscriptomicsLGR5 positivity defines stem-like cells in colorectal cancer
To further elucidate the role of the intestinal stem cell marker Leucine-rich-repeat-containing G-protein-coupled receptor 5 (LGR5) in colorectal cancer (CRC), we exposed Lgr5-EGFP-IRES-Cre-ERT2 mice to azoxymethane/dextrane sodium sulfate (AOM/DSS) which induces inflammation-driven colon tumors. Tu...
ORGANISM(S): Mus musculus 
2013-04-19 | E-GEOD-46200 | biostudies-arrayexpress
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