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UnknownGenome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma.
Not available
S-EPMC3209696 | biostudies-literature
UnknownPediatric Brain Tumors: Innovative Genomic Information Is Transforming the Diagnostic and Clinical Landscape.
Not available
S-EPMC4567701 | biostudies-literature
UnknownPhase I trial of MK-0752 in children with refractory CNS malignancies: a pediatric brain tumor consortium study.
Not available
S-EPMC3179253 | biostudies-literature
UnknownVismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.
Not available
S-EPMC4534527 | biostudies-literature
TranscriptomicsGenotype profiling of a primitive neuroectodermal tumour identifies a non-constitutive chr19q13.41 amplicon
Primitive neuro-ectodermal tumours (PNET) of the supratentorial region are rare, highly malignant embryonal brain tumours affecting young children. Although supratentorial PNET (sPNET) are histologically similar to infratentorial PNET/medulloblastoma, sPNET have more aggressive clinical phenotypes, ...
ORGANISM(S): Homo sapiens 
2010-04-03 | E-GEOD-14248 | biostudies-arrayexpress
UnknownExtensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial.
Not available
S-EPMC9153369 | biostudies-literature
TranscriptomicsGenotype profiling of primitive neuroectodermal tumours (250K_Nsp_SNP and 250K_Sty_SNP)
Primitive neuro-ectodermal tumours (PNET) of the supratentorial region are rare, highly malignant embryonal brain tumours affecting young children. Although supratentorial PNET (sPNET) are histologically similar to infratentorial PNET/medulloblastoma, sPNET have more aggressive clinical phenotypes, ...
ORGANISM(S): Homo sapiens 
2009-12-21 | E-GEOD-14087 | biostudies-arrayexpress
TranscriptomicsGenome-wide Analyses of Diffuse Intrinsic Pontine Gliomas
Purpose: More than 90% of children with diffuse intrinsic pontine glioma (DIPG) die within 2 years of diagnosis. There is a dire need to identify therapeutic targets, however lack of patient material for research has limited progress. We evaluated a large cohort of diffuse intrinsic pontine gliomas ...
ORGANISM(S): Homo sapiens 
2011-09-20 | E-GEOD-26576 | biostudies-arrayexpress
TranscriptomicsIntegrated molecular genetic profiling of pediatric-high grade gliomas reveals key differences with adult disease
Purpose: To define copy number alterations and gene expression signatures underlying pediatric high-grade glioma (HGG). Patients and Methods: We conducted a high-resolution analysis of genomic imbalances in 78 de novo pediatric HGG, including 7 diffuse intrinsic pontine gliomas, and 10 HGG cases ar...
ORGANISM(S): Homo sapiens 
2010-06-15 | E-GEOD-19578 | biostudies-arrayexpress
UnknownTherapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
Not available
S-EPMC4962737 | biostudies-literature
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