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Our goal was to identify differentially expressed genes in Drosophila muscle when misexpressing the human PAX-FKHR fusion oncoprotein. Using the GAL4-UAS expression system, PAX7-FKHR was misexpressed in differentiating muscle. After 2-3 days of expression larval animals were collected, dissected to ...
ORGANISM(S): Drosophila melanogaster 
Activation of Sonic Hedgehog signaling through expression of a constitutively active Smoothened allele under control of an aP2 adipocyte-restricted transgene in mice gives rise to aggressive skeletal muscle tumors that display the histologic and molecular characteristics of human embryonal rhabdomyo...
ORGANISM(S): Mus musculus 
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