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ProteomicsDiagnostic biomarkers of hepatocellular carcinoma based on 4D label-free quantitative proteomics analysis.
Hepatocellular carcinoma (HCC) carries a poor prognosis and poses a serious threat to global health. Although early diagnosis and treatment can significantly reduce mortality, biomarkers of early HCC are lacking. This pilot study used 4D label-free quantitative proteomics to compare the proteomes of...
ORGANISM(S): Homo Sapiens 
PXD041811 |
ProteomicsPhospho-proteomics enables classification of cancer subtypes and nomination of druggable kinases for individual patients of diffuse-type gastric cancer
The diffuse-type gastric cancer (DGC) constitutes a subgroup of gastric cancer with poor prognosis and no effective molecular therapies. Here, we report a phosphoproteomic landscape of DGC derived from 83 tumors together with their nearby tissues. Based on phosphorylation, DGC could be classified in...
ORGANISM(S): Homo Sapiens 
2020-03-31 | PXD018293 |
ProteomicsMulti-omic analysis reveals a CAF-stemness-governed classification in HCC liver transplant recipients
In patients with hepatocellular carcinoma (HCC) meeting the Milan criteria, liver transplantation (LT) is an effective therapy. This study aims to define the survival-related molecular biological features helping precisely identifying the patients with HCC beyond the Milan criteria who have acceptab...
ORGANISM(S): Homo Sapiens 
2025-02-24 | PXD061119 |
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