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TranscriptomicsA Role for Small RNAs in DNA Double-Strand Break Repair
Here we identify a novel class of small RNAs that are ~21-nucleotide in length and are produced from the sequences in the vicinity of DNA double strand break (DSB) sites in Arabidopsis and humans. We named them diRNAs for DSB-induced small RNAs. In Arabidopsis, the biogenesis of diRNAs requires the ...
ORGANISM(S): Arabidopsis thaliana 
2012-03-26 | E-GEOD-36338 | biostudies-arrayexpress
TranscriptomicsRNA Subcellular Localization by Paired End diTag Sequencing from ENCODE/GIS
This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Yijun Ruan mailto:ruanyj@gis.a-star.edu.sg). If you have questions about the Genome Browser track associated with this data, contact ENCODE (mailto:genome@soe.ucsc.edu). This track i...
ORGANISM(S): Homo sapiens 
2011-11-10 | E-GEOD-33600 | biostudies-arrayexpress
GenomicsLong Span DNA Paired-End-Tag (DNA-PET) Sequencing Strategy for the Interrogation of Genomic Structural Mutations
Structural variations (SVs) contribute significantly to the variability of the human genome and extensive genomic rearrangements are a hallmark of cancer. Genomic DNA paired-end-tag (DNA-PET) sequencing is an attractive approach to identify genomic SVs. The current application of PET sequencing with...
ORGANISM(S): Homo sapiens 
2012-10-04 | E-GEOD-32674 | biostudies-arrayexpress
GenomicsComprehensive Long Span Paired-End-Tag Mapping Reveals Characteristic Patterns of Structural Variations in Epithelial Cancer Genomes
Somatic genome rearrangements are thought to play important roles in cancer development. We optimized a long span paired-end-tag (PET) sequencing approach using 10 Kb genomic DNA inserts to study human genome structural variations (SVs). The use of 10 Kb insert size allows the identification of brea...
ORGANISM(S): Homo sapiens 
2011-04-06 | E-GEOD-26954 | biostudies-arrayexpress
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