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GenomicsImproved tagmentation-based whole genome bisulfite sequencing for input DNA from less than 100 cells
We improved the tagmentation-based whole genome bisulfite sequencing technology, enabling stable library construction with complexity from minimally 0.5ng of initial genomic DNA, which equals less than 100 cells. This new approach is highly attractive for the complete methylome analysis of very limi...
ORGANISM(S): Oryza sativa 
2014-05-01 | E-GEOD-57062 | biostudies-arrayexpress
UnknownBrain tumor feature extraction and edge enhancement algorithm based on U-Net network.
Not available
S-EPMC10687284 | biostudies-literature
TranscriptomicsClassification of cancer cell lines using a promoter-targeted liquid hybridization capture-based bisulfite sequencing approach
DNA methylation plays a significant role in assuring cell identity, thus potentiating its application in molecular classification of cancers in respect of tissue origins or clinically and aetiologically distinct subtypes. In this study, we adapted our liquid hybridization capture-based bisulfite seq...
ORGANISM(S): Homo sapiens 
2014-02-19 | E-GEOD-44866 | biostudies-arrayexpress
GenomicsDirect ChIP-bisulfite sequencing reveals a role of H3K27me3 mediating aberrant hypermethylation of promoter CpG islands in cancer cells (ChIP-BS)
The model describing that aberrant CpG island (CGI) methylation leads to transcription repression of tumor suppressor genes and thereby is implicated in tumor progression has been established in many cancers. However, recent studies indicated aberrantly hypermethylated genes in multiple cancers are ...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-43094 | biostudies-arrayexpress
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