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TranscriptomicsSecreted Frizzled-Related Protein 5 is Downregulated in Obesity and Promotes β-Cell Proliferation [10 days]
Obesity is associated with an increase in β-cell mass in response to the rising demand for insulin. β-cell plasticity is essential to maintaining glucose homeostasis, however, the cellular and molecular mechanisms by which β-cell mass is regulated remain poorly understood. Recently, we described the...
ORGANISM(S): Rattus norvegicus 
2014-10-10 | E-GEOD-44045 | biostudies-arrayexpress
TranscriptomicsSecreted Frizzled-Related Protein 5 is Downregulated in Obesity and Promotes ?-Cell Proliferation [30 days]
Obesity is associated with an increase in ?-cell mass in response to the rising demand for insulin. ?-cell plasticity is essential to maintaining glucose homeostasis, however, the cellular and molecular mechanisms by which ?-cell mass is regulated remain poorly understood. Recently, we described the...
ORGANISM(S): Rattus norvegicus 
2014-10-10 | E-GEOD-44046 | biostudies-arrayexpress
TranscriptomicsSecreted Frizzled-Related Protein 5 is Downregulated in Obesity and Promotes ?-Cell Proliferation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Rattus norvegicus 
2014-10-10 | E-GEOD-44047 | biostudies-arrayexpress
TranscriptomicsReduced a-MSH underlies hypothalamic endoplasmic reticulum stress-induced hepatic gluconeogenesis
Alterations in endoplasmic reticulum (ER) homeostasis have been implicated in the pathophysiology of obesity and type-2 diabetes (T2D). Acute ER stress induction in the hypothalamus produces glucose metabolism perturbations. However, the neurobiological basis linking hypothalamic ER stress with abno...
ORGANISM(S): Mus musculus 
2015-06-18 | E-GEOD-62263 | biostudies-arrayexpress
UnknownEvaluating the implementation of community engagement guidelines (EVALUA GPS project): a study protocol.
Not available
S-EPMC9950881 | biostudies-literature
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