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MetabolomicsOn-line targeted metabolomics for real-time monitoring of relevant compounds in fermentation processes
Fermentation monitoring is a powerful tool for bioprocess development and optimisation. On-line metabolomics is a technology that is starting to gain attention as a bioprocess monitoring tool, allowing the direct measurement of many compounds in the fermentation broth at a very high time resolution....
2024-03-05 | MTBLS7889 | MetaboLights
MetabolomicsStreamlined identification of strain engineering targets for bioprocess improvement using metabolic pathway enrichment analysis
Metabolomics is a powerful tool for the identification of genetic targets for bioprocess optimisation. However, in most cases, only the biosynthetic pathway directed to product formation is analysed, limiting the identification of these targets. Some studies have used untargeted metabolomics, allowi...
2023-08-31 | MTBLS6667 | MetaboLights
MetabolomicsOn-line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process
The real-time monitoring of metabolites (RTMet) is instrumental for the industrial production of biobased fermentation products. This study shows the first application of untargeted on-line metabolomics for the monitoring of undiluted fermentation broth samples taken automatically from a 5 L bioreac...
2023-04-26 | MTBLS5197 | MetaboLights
GenomicsAnalysis of whole-genome copy-number variation in Crohn's disease fistula tissue
Background: CrohnM-bM-^@M-^Ys disease is presently an incurable inflammatory bowel disease. Fistulae are extensions of the intestinal tract that may form connections with other organs. These are a common complication of CrohnM-bM-^@M-^Ys disease affecting up to 50% of patients with the most common i...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-44275 | biostudies-arrayexpress
TranscriptomicsData integration from two microarray platforms identifies genetic inactivation of RIC8A in a breast cancer cell line
Using array comparative genomic hybridization (aCGH), a large number of deleted genomic regions have been identified in human cancers. However, subsequent efforts to identify target genes selected for inactivation in these regions have often been challenging. We integrated here genome-wide copy numb...
ORGANISM(S): Homo sapiens 
2010-06-19 | E-GEOD-15477 | biostudies-arrayexpress
UnknownImmune response to JC virus T antigen in patients with and without colorectal neoplasia.
Not available
S-EPMC5515464 | biostudies-literature
TranscriptomicsDetection of non-coding deletion CNVs upstream to FOXF1 [Agilent-022084]
Genomic copy number analysis in patients with ACD/MPV. An unanticipated and tremendous amount of the non-coding sequences of the human genome are transcribed. Long non-coding RNAs (lncRNAs) are non-protein coding transcripts longer than 200 nucleotides and their functions remain enigmatic. We dem...
ORGANISM(S): Homo sapiens 
2012-07-05 | E-GEOD-38978 | biostudies-arrayexpress
UnknownPredicting and validating a model of suppressor of IKKepsilon through biophysical characterization.
Not available
S-EPMC6635840 | biostudies-literature
UnknownA proteomic analysis of an in vitro knock-out of miR-200c.
Not available
S-EPMC5931999 | biostudies-literature
UnknownA Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons.
Not available
S-EPMC6396380 | biostudies-literature
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