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GenomicsNSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming [ChIP]
NSD2 (also named MMSET and WHSC1) is a histone lysine methyltransferase that is implicated in diverse diseases and commonly overexpressed in multiple myeloma due to a recurrent t(4;14) chromosomal translocation. However, the precise catalytic activity of NSD2 is obscure, preventing progress in unde...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-29146 | biostudies-arrayexpress
TranscriptomicsNSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming [RNAi]
NSD2 (also named MMSET and WHSC1) is a histone lysine methyltransferase that is implicated in diverse diseases and commonly overexpressed in multiple myeloma due to a recurrent t(4;14) chromosomal translocation. However, the precise catalytic activity of NSD2 is obscure, preventing progress in unde...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-29147 | biostudies-arrayexpress
TranscriptomicsNSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming [TKO]
NSD2 (also named MMSET and WHSC1) is a histone lysine methyltransferase that is implicated in diverse diseases and commonly overexpressed in multiple myeloma due to a recurrent t(4;14) chromosomal translocation. However, the precise catalytic activity of NSD2 is obscure, preventing progress in unde...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-29148 | biostudies-arrayexpress
TranscriptomicsNSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming [Transduction]
NSD2 (also named MMSET and WHSC1) is a histone lysine methyltransferase that is implicated in diverse diseases and commonly overexpressed in multiple myeloma due to a recurrent t(4;14) chromosomal translocation. However, the precise catalytic activity of NSD2 is obscure, preventing progress in unde...
ORGANISM(S): Mus musculus 
2011-11-29 | E-GEOD-29150 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq of Endometrial organoids treated with NOTCH or WNT inhibitors in a time course of Estrogen and Progesterone stimulation
We performed single-cell RNA-sequencing of 3D endometrial organoid cultures in order to dissect the signaling pathways that determine cell fate of epithelial lineages. Every time course was obtained in a background that either included or did not include ovarian hormones stimulation, which emulates ...
ORGANISM(S): Homo sapiens 
2021-07-21 | E-MTAB-10283 | biostudies-arrayexpress
UnknownA circular engineered sortase for interrogating histone H3 in chromatin.
Not available
S-EPMC11451751 | biostudies-literature
TranscriptomicsRegions of XY homology in the pig X chromosome and the boundary of the pseudoautosomal region
Background Sex chromosomes are subject to evolutionary pressures distinct from the remainder of the genome, shaping their structure and sequence content. We are interested in the sex chromosomes of domestic pigs (Sus scrofa), how their structure and gene content compares and contrasts with other mam...
ORGANISM(S): Sus scrofa 
2012-08-30 | E-GEOD-40244 | biostudies-arrayexpress
UnknownProteome-wide prediction of acetylation substrates.
Not available
S-EPMC2728972 | biostudies-literature
UnknownTargeting acetyl-CoA metabolism attenuates the formation of fear memories through reduced activity-dependent histone acetylation.
Not available
S-EPMC9371679 | biostudies-literature
UnknownCircular Engineered Sortase for Interrogating Histone H3 in Chromatin.
Not available
S-EPMC11638967 | biostudies-literature
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